DIAPH3-AS1

Summary

DIAPH3-AS1 (DIAPH3 antisense RNA 1, HGNC:39915) is a long non-coding RNA gene on chromosome 13q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39915
Approved symbol	DIAPH3-AS1
Name	DIAPH3 antisense RNA 1
Location	13q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227528
Ensembl biotype	lncRNA
Entrez	100874195
RNAcentral	URS000075BEA5 — lncRNA, 512 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000422052, ENST00000432995, ENST00000435636, ENST00000671612, ENST00000826397, ENST00000826398, ENST00000826399, ENST00000826400, ENST00000826401

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422052 — 4 exons

Exon	Start	End
ENSE00001641600	60020921	60021008
ENSE00001654456	60044196	60044357
ENSE00001772623	60042681	60042789
ENSE00004237237	60013258	60013371

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 95.76.

Top tissues by expression

188 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	95.76	gold quality
tendon of biceps brachii	UBERON:0008188	95.13	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.45	gold quality
buccal mucosa cell	CL:0002336	90.42	gold quality
tendon	UBERON:0000043	86.21	silver quality
left testis	UBERON:0004533	85.31	gold quality
right testis	UBERON:0004534	84.18	gold quality
testis	UBERON:0000473	82.42	gold quality
sperm	CL:0000019	76.54	gold quality
parotid gland	UBERON:0001831	75.26	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	68.36	gold quality
esophagus squamous epithelium	UBERON:0006920	66.91	gold quality
myocardium	UBERON:0002349	66.89	gold quality
secondary oocyte	CL:0000655	65.76	gold quality
visceral pleura	UBERON:0002401	63.15	gold quality
parietal pleura	UBERON:0002400	62.86	gold quality
calcaneal tendon	UBERON:0003701	61.94	gold quality
heart right ventricle	UBERON:0002080	61.73	gold quality
jejunal mucosa	UBERON:0000399	61.06	gold quality
tibia	UBERON:0000979	60.41	gold quality
cartilage tissue	UBERON:0002418	59.40	gold quality
monocyte	CL:0000576	59.19	gold quality
postcentral gyrus	UBERON:0002581	59.01	gold quality
vastus lateralis	UBERON:0001379	58.88	gold quality
skeletal muscle tissue	UBERON:0001134	58.71	gold quality
prefrontal cortex	UBERON:0000451	58.60	gold quality
metanephros	UBERON:0000081	58.25	gold quality
jejunum	UBERON:0002115	58.20	gold quality
superior frontal gyrus	UBERON:0002661	58.12	gold quality
quadriceps femoris	UBERON:0001377	58.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.