DICER1-AS1

Summary

DICER1-AS1 (DICER1 antisense RNA 1, HGNC:43017) is a long non-coding RNA gene on chromosome 14q32.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43017
Approved symbol	DICER1-AS1
Name	DICER1 antisense RNA 1
Location	14q32.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ45244
Ensembl gene	ENSG00000235706
Ensembl biotype	lncRNA
Entrez	400242
RNAcentral	URS000075A74D — lncRNA, 830 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000435343, ENST00000439819, ENST00000439999, ENST00000554631, ENST00000654147, ENST00000661445, ENST00000671073, ENST00000692703, ENST00000693197, ENST00000750374, ENST00000750375, ENST00000750376, ENST00000750377, ENST00000750378, ENST00000750379, ENST00000750380, ENST00000750381, ENST00000750382, ENST00000750383, ENST00000750384, ENST00000750385, ENST00000750386, ENST00000750387

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435343 — 4 exons

Exon	Start	End
ENSE00001690046	95157677	95157858
ENSE00001714092	95158876	95159035
ENSE00001770362	95179504	95179936
ENSE00001787875	95158193	95158234

Expression profiles

Bgee: expression breadth ubiquitous, 209 present calls, max score 96.85.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.2542 / max 62.7745, expressed in 1207 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
141284	4.2542	1207

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	96.85	gold quality
oviduct epithelium	UBERON:0004804	96.77	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	90.80	gold quality
adenohypophysis	UBERON:0002196	89.22	gold quality
pituitary gland	UBERON:0000007	88.85	gold quality
spinal cord	UBERON:0002240	88.15	gold quality
hypothalamus	UBERON:0001898	86.77	gold quality
gastrocnemius	UBERON:0001388	86.64	gold quality
tendon of biceps brachii	UBERON:0008188	86.35	gold quality
right hemisphere of cerebellum	UBERON:0014890	86.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	86.33	gold quality
muscle of leg	UBERON:0001383	86.18	gold quality
cerebellar hemisphere	UBERON:0002245	86.09	gold quality
fallopian tube	UBERON:0003889	86.04	gold quality
amygdala	UBERON:0001876	86.00	gold quality
cerebellar cortex	UBERON:0002129	85.89	gold quality
left testis	UBERON:0004533	85.81	gold quality
right frontal lobe	UBERON:0002810	85.73	gold quality
right testis	UBERON:0004534	85.68	gold quality
nucleus accumbens	UBERON:0001882	85.62	gold quality
putamen	UBERON:0001874	85.35	gold quality
Brodmann (1909) area 9	UBERON:0013540	85.29	gold quality
anterior cingulate cortex	UBERON:0009835	85.28	gold quality
caudate nucleus	UBERON:0001873	85.09	gold quality
right adrenal gland	UBERON:0001233	84.65	gold quality
cerebellum	UBERON:0002037	84.40	gold quality
apex of heart	UBERON:0002098	84.38	gold quality
left lobe of thyroid gland	UBERON:0001120	84.17	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.15	gold quality
right adrenal gland cortex	UBERON:0035827	84.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.87

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA DICER1-AS1 promotes colorectal cancer progression by activating the MAPK/ERK signaling pathway through sponging miR-650. (PMID:36708020)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.