DIP2A-IT1

Summary

DIP2A-IT1 (DIP2A intronic transcript 1, HGNC:41430) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41430
Approved symbol	DIP2A-IT1
Name	DIP2A intronic transcript 1
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223692
Ensembl biotype	lncRNA
Entrez	100862692
RNAcentral	URS000053769C — lncRNA, 428 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000442434

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442434 — 4 exons

Exon	Start	End
ENSE00001681675	46469146	46469306
ENSE00001740202	46462471	46462522
ENSE00001765964	46463066	46463228
ENSE00001790677	46462712	46462763

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 79.63.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.63	gold quality
bone marrow	UBERON:0002371	78.45	gold quality
bone marrow cell	CL:0002092	75.37	gold quality
monocyte	CL:0000576	72.30	gold quality
leukocyte	CL:0000738	71.46	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.66	gold quality
ventricular zone	UBERON:0003053	68.96	gold quality
ganglionic eminence	UBERON:0004023	68.45	gold quality
colonic epithelium	UBERON:0000397	67.85	gold quality
corpus callosum	UBERON:0002336	66.34	gold quality
skeletal muscle tissue	UBERON:0001134	65.74	gold quality
blood	UBERON:0000178	65.09	gold quality
gall bladder	UBERON:0002110	64.93	gold quality
smooth muscle tissue	UBERON:0001135	63.32	gold quality
vermiform appendix	UBERON:0001154	62.11	gold quality
lymph node	UBERON:0000029	60.21	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.19	gold quality
adrenal tissue	UBERON:0018303	59.81	gold quality
muscle of leg	UBERON:0001383	59.46	gold quality
islet of Langerhans	UBERON:0000006	59.28	gold quality
tonsil	UBERON:0002372	59.04	gold quality
gastrocnemius	UBERON:0001388	58.98	gold quality
apex of heart	UBERON:0002098	58.93	gold quality
prefrontal cortex	UBERON:0000451	58.61	gold quality
sural nerve	UBERON:0015488	58.50	silver quality
duodenum	UBERON:0002114	58.26	gold quality
calcaneal tendon	UBERON:0003701	58.00	gold quality
endometrium	UBERON:0001295	57.06	gold quality
right atrium auricular region	UBERON:0006631	57.04	gold quality
heart	UBERON:0000948	56.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.