DIS3L-AS1

Summary

DIS3L-AS1 (DIS3L antisense RNA 1, HGNC:55369) is a long non-coding RNA gene on chromosome 15q22.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55369
Approved symbol	DIS3L-AS1
Name	DIS3L antisense RNA 1
Location	15q22.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261318
Ensembl biotype	lncRNA
Entrez	105370868
RNAcentral	URS00026A1FF6 — lncRNA, 1122 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000564269, ENST00000784663

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564269 — 2 exons

Exon	Start	End
ENSE00002613080	66278498	66279043
ENSE00004159621	66293326	66293492

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 94.16.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.16	gold quality
left testis	UBERON:0004533	66.13	gold quality
testis	UBERON:0000473	65.38	gold quality
right testis	UBERON:0004534	64.44	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.26	gold quality
skeletal muscle tissue	UBERON:0001134	59.33	gold quality
superior frontal gyrus	UBERON:0002661	57.85	gold quality
monocyte	CL:0000576	56.63	gold quality
right ovary	UBERON:0002118	56.23	gold quality
left adrenal gland cortex	UBERON:0035825	55.61	gold quality
ovary	UBERON:0000992	55.31	gold quality
islet of Langerhans	UBERON:0000006	55.06	gold quality
left ovary	UBERON:0002119	54.99	gold quality
lower esophagus mucosa	UBERON:0035834	54.34	gold quality
prefrontal cortex	UBERON:0000451	54.20	gold quality
left uterine tube	UBERON:0001303	54.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.22	gold quality
body of uterus	UBERON:0009853	52.99	gold quality
bone marrow	UBERON:0002371	52.97	gold quality
right uterine tube	UBERON:0001302	52.88	gold quality
cortex of kidney	UBERON:0001225	52.59	gold quality
endocervix	UBERON:0000458	52.16	gold quality
uterine cervix	UBERON:0000002	51.45	gold quality
smooth muscle tissue	UBERON:0001135	51.44	gold quality
blood	UBERON:0000178	51.12	silver quality
metanephros cortex	UBERON:0010533	50.82	gold quality
vermiform appendix	UBERON:0001154	50.54	gold quality
muscle of leg	UBERON:0001383	50.47	gold quality
myometrium	UBERON:0001296	50.45	gold quality
fallopian tube	UBERON:0003889	50.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.