DKK2-AS1

Summary

DKK2-AS1 (DKK2 antisense RNA 1, HGNC:58864) is a long non-coding RNA gene on chromosome 4q24-q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58864
Approved symbol	DKK2-AS1
Name	DKK2 antisense RNA 1
Location	4q24-q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286147
Ensembl biotype	lncRNA
Entrez	105377356

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000650850

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000650850 — 11 exons

Exon	Start	End
ENSE00003843856	106934679	106938640
ENSE00003844191	106627034	106627133
ENSE00003844507	106917079	106917252
ENSE00003844518	106707338	106707438
ENSE00003844702	106920071	106920188
ENSE00003844915	106641948	106642014
ENSE00003845991	106525401	106525501
ENSE00003847562	106789236	106789301
ENSE00003847760	106911058	106911090
ENSE00003848312	106914522	106914642
ENSE00003848627	106620376	106620425

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 90.24.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.24	gold quality
uterine cervix	UBERON:0000002	80.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.26	silver quality
liver	UBERON:0002107	71.07	gold quality
skeletal muscle tissue	UBERON:0001134	70.78	gold quality
urinary bladder	UBERON:0001255	70.53	gold quality
tonsil	UBERON:0002372	69.94	gold quality
bone marrow cell	CL:0002092	68.74	silver quality
sural nerve	UBERON:0015488	68.37	gold quality
colonic epithelium	UBERON:0000397	68.14	silver quality
placenta	UBERON:0001987	65.80	gold quality
thoracic mammary gland	UBERON:0005200	62.72	gold quality
ventricular zone	UBERON:0003053	60.77	gold quality
cortical plate	UBERON:0005343	60.70	silver quality
prostate gland	UBERON:0002367	59.20	silver quality
ganglionic eminence	UBERON:0004023	59.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.83	gold quality
blood	UBERON:0000178	57.37	gold quality
kidney	UBERON:0002113	57.23	gold quality
pancreas	UBERON:0001264	56.67	silver quality
lung	UBERON:0002048	55.99	gold quality
cortex of kidney	UBERON:0001225	55.08	gold quality
monocyte	CL:0000576	52.92	silver quality
stomach	UBERON:0000945	52.01	silver quality
adrenal gland	UBERON:0002369	51.63	silver quality
stromal cell of endometrium	CL:0002255	51.05	silver quality
small intestine	UBERON:0002108	50.97	silver quality
calcaneal tendon	UBERON:0003701	50.68	silver quality
prefrontal cortex	UBERON:0000451	50.22	gold quality
frontal cortex	UBERON:0001870	49.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.