DKK2-AS2

Summary

DKK2-AS2 (DKK2 antisense RNA 2, HGNC:58865) is a long non-coding RNA gene on chromosome 4q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58865
Approved symbol	DKK2-AS2
Name	DKK2 antisense RNA 2
Location	4q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251081
Ensembl biotype	lncRNA
Entrez	102725220

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000508555, ENST00000736477, ENST00000736478

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508555 — 2 exons

Exon	Start	End
ENSE00002060753	107258700	107258874
ENSE00002066775	107301489	107301870

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 83.66.

Top tissues by expression

179 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.66	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.02	silver quality
hindlimb stylopod muscle	UBERON:0004252	73.11	gold quality
left testis	UBERON:0004533	72.43	gold quality
right testis	UBERON:0004534	71.89	gold quality
testis	UBERON:0000473	69.91	gold quality
monocyte	CL:0000576	56.27	gold quality
muscle of leg	UBERON:0001383	54.80	gold quality
gastrocnemius	UBERON:0001388	54.33	gold quality
gall bladder	UBERON:0002110	54.20	gold quality
islet of Langerhans	UBERON:0000006	53.60	gold quality
calcaneal tendon	UBERON:0003701	51.19	silver quality
upper leg skin	UBERON:0004262	49.78	silver quality
right coronary artery	UBERON:0001625	48.64	gold quality
cerebellar vermis	UBERON:0004720	48.63	gold quality
body of pancreas	UBERON:0001150	47.94	gold quality
pancreas	UBERON:0001264	47.57	gold quality
adrenal tissue	UBERON:0018303	46.45	silver quality
prostate gland	UBERON:0002367	45.92	gold quality
tibial artery	UBERON:0007610	45.61	silver quality
lymph node	UBERON:0000029	45.54	gold quality
heart left ventricle	UBERON:0002084	44.77	gold quality
anatomical system	UBERON:0000467	44.76	gold quality
multicellular organism	UBERON:0000468	44.54	gold quality
material anatomical entity	UBERON:0000465	44.53	gold quality
right atrium auricular region	UBERON:0006631	44.16	silver quality
ectocervix	UBERON:0012249	44.06	gold quality
bone marrow	UBERON:0002371	44.05	silver quality
aorta	UBERON:0000947	44.02	silver quality
primary visual cortex	UBERON:0002436	43.80	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.