DLGAP1-AS3

Summary

DLGAP1-AS3 (DLGAP1 antisense RNA 3, HGNC:27317) is a long non-coding RNA gene on chromosome 18p11.31.

Predicted to enable U4 snRNA binding activity. Predicted to be involved in formation of quadruple SL/U4/U5/U6 snRNP and spliceosomal tri-snRNP complex assembly. Predicted to be part of U4/U6 x U5 tri-snRNP complex and U6 snRNP.

Source: NCBI Gene 201477 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27317
Approved symbol	DLGAP1-AS3
Name	DLGAP1 antisense RNA 3
Location	18p11.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263724
Ensembl biotype	lncRNA
Entrez	201477
RNAcentral	URS00004303C7 — lncRNA, 1258 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000577649, ENST00000583571, ENST00000666095, ENST00000667062, ENST00000668905

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577649 — 3 exons

Exon	Start	End
ENSE00002696265	3878180	3878291
ENSE00002711622	3895771	3896003
ENSE00002725502	3896157	3897069

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 77.58.

Top tissues by expression

212 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.58	gold quality
gall bladder	UBERON:0002110	66.77	gold quality
prefrontal cortex	UBERON:0000451	66.49	gold quality
cortical plate	UBERON:0005343	66.26	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.29	gold quality
adenohypophysis	UBERON:0002196	65.08	gold quality
right frontal lobe	UBERON:0002810	64.61	gold quality
corpus epididymis	UBERON:0004359	63.89	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.35	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.62	gold quality
frontal cortex	UBERON:0001870	61.17	gold quality
neocortex	UBERON:0001950	60.34	gold quality
primary visual cortex	UBERON:0002436	58.47	gold quality
leukocyte	CL:0000738	58.31	gold quality
monocyte	CL:0000576	58.26	gold quality
anterior cingulate cortex	UBERON:0009835	58.08	gold quality
seminal vesicle	UBERON:0000998	57.67	gold quality
endometrium	UBERON:0001295	57.03	gold quality
cerebral cortex	UBERON:0000956	56.51	gold quality
ganglionic eminence	UBERON:0004023	56.47	silver quality
right lobe of liver	UBERON:0001114	56.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.75	silver quality
cerebellar cortex	UBERON:0002129	53.96	gold quality
granulocyte	CL:0000094	53.91	gold quality
cerebellar hemisphere	UBERON:0002245	53.82	gold quality
occipital lobe	UBERON:0002021	53.80	gold quality
right hemisphere of cerebellum	UBERON:0014890	53.44	gold quality
cerebellum	UBERON:0002037	53.07	gold quality
uterus	UBERON:0000995	52.29	gold quality
forebrain	UBERON:0001890	51.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.