DLGAP4-AS1
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Also known as CCAT7
Summary
DLGAP4-AS1 (DLGAP4 antisense RNA 1, HGNC:51223) is a long non-coding RNA gene on chromosome 20q11.23.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:51223 |
| Approved symbol | DLGAP4-AS1 |
| Name | DLGAP4 antisense RNA 1 |
| Location | 20q11.23 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | CCAT7 |
| Ensembl gene | ENSG00000232907 |
| Ensembl biotype | lncRNA |
| Entrez | 101926987 |
| RNAcentral | URS000075AB8D — lncRNA, 1241 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 13 — 13 lncRNA
ENST00000425233, ENST00000433238, ENST00000439595, ENST00000559455, ENST00000559804, ENST00000656949, ENST00000793269, ENST00000793270, ENST00000793271, ENST00000793272, ENST00000793273, ENST00000793274, ENST00000793275
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000425233 — 7 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001611134 | 36510880 | 36511032 |
| ENSE00001701841 | 36571441 | 36571543 |
| ENSE00003706338 | 36525501 | 36525566 |
| ENSE00003924594 | 36507705 | 36508274 |
| ENSE00003934548 | 36512485 | 36512725 |
| ENSE00004175984 | 36527724 | 36527924 |
| ENSE00004175986 | 36572912 | 36573410 |
Expression profiles
Bgee: expression breadth ubiquitous, 161 present calls, max score 82.14.
FANTOM5 (CAGE): breadth broad, TPM avg 0.6767 / max 13.5156, expressed in 343 samples.
FANTOM5 promoters (2 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 187121 | 0.6085 | 327 |
| 187120 | 0.0682 | 32 |
Top tissues by expression
246 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 82.14 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 79.12 | gold quality |
| left testis | UBERON:0004533 | 77.11 | gold quality |
| right testis | UBERON:0004534 | 76.51 | gold quality |
| sural nerve | UBERON:0015488 | 75.60 | gold quality |
| testis | UBERON:0000473 | 75.35 | gold quality |
| buccal mucosa cell | CL:0002336 | 72.64 | gold quality |
| bone marrow cell | CL:0002092 | 71.59 | silver quality |
| granulocyte | CL:0000094 | 71.06 | gold quality |
| colonic epithelium | UBERON:0000397 | 69.91 | gold quality |
| apex of heart | UBERON:0002098 | 68.40 | gold quality |
| mucosa of stomach | UBERON:0001199 | 68.19 | gold quality |
| right lobe of liver | UBERON:0001114 | 67.82 | gold quality |
| sperm | CL:0000019 | 67.67 | silver quality |
| hindlimb stylopod muscle | UBERON:0004252 | 67.51 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 67.13 | gold quality |
| thyroid gland | UBERON:0002046 | 66.84 | gold quality |
| adrenal tissue | UBERON:0018303 | 66.72 | gold quality |
| spleen | UBERON:0002106 | 66.67 | gold quality |
| lower esophagus mucosa | UBERON:0035834 | 66.64 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 66.47 | gold quality |
| ganglionic eminence | UBERON:0004023 | 66.25 | gold quality |
| popliteal artery | UBERON:0002250 | 65.53 | gold quality |
| tibial artery | UBERON:0007610 | 65.51 | gold quality |
| aorta | UBERON:0000947 | 64.85 | gold quality |
| ascending aorta | UBERON:0001496 | 64.53 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 64.34 | gold quality |
| thoracic aorta | UBERON:0001515 | 64.29 | gold quality |
| tendon of biceps brachii | UBERON:0008188 | 63.76 | gold quality |
| stromal cell of endometrium | CL:0002255 | 63.63 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 3.58 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): megacystis-microcolon-intestinal hypoperistalsis syndrome 4, visceral myopathy 1