DLX2-DT

Summary

DLX2-DT (DLX2 divergent transcript, HGNC:50638) is a long non-coding RNA gene on chromosome 2q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50638
Approved symbol	DLX2-DT
Name	DLX2 divergent transcript
Location	2q31.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00003049
Ensembl gene	ENSG00000236651
Ensembl biotype	lncRNA
Entrez	104326193
RNAcentral	URS00003976A5 — lncRNA, 950 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000448117, ENST00000662340, ENST00000667725, ENST00000715288

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000448117 — 5 exons

Exon	Start	End
ENSE00001648538	172103006	172103268
ENSE00001667405	172109790	172109982
ENSE00001708595	172103938	172104032
ENSE00001718120	172105883	172106200
ENSE00001752487	172108902	172108982

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 50.26.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
prefrontal cortex	UBERON:0000451	50.26	gold quality
monocyte	CL:0000576	49.49	silver quality
blood	UBERON:0000178	48.34	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.82	silver quality
cerebral cortex	UBERON:0000956	45.84	gold quality
islet of Langerhans	UBERON:0000006	45.08	silver quality
prostate gland	UBERON:0002367	44.69	silver quality
fallopian tube	UBERON:0003889	44.51	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	43.71	silver quality
skin of leg	UBERON:0001511	43.33	gold quality
right hemisphere of cerebellum	UBERON:0014890	43.28	gold quality
skin of abdomen	UBERON:0001416	43.22	gold quality
tibial artery	UBERON:0007610	42.98	silver quality
putamen	UBERON:0001874	42.80	gold quality
temporal lobe	UBERON:0001871	42.42	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.37	silver quality
thyroid gland	UBERON:0002046	42.16	silver quality
ascending aorta	UBERON:0001496	41.36	silver quality
Ammon’s horn	UBERON:0001954	40.85	silver quality
left testis	UBERON:0004533	40.57	gold quality
caudate nucleus	UBERON:0001873	40.47	gold quality
testis	UBERON:0000473	40.36	gold quality
lower esophagus muscularis layer	UBERON:0035833	39.88	silver quality
amygdala	UBERON:0001876	39.63	silver quality
endometrium	UBERON:0001295	39.21	silver quality
right testis	UBERON:0004534	38.91	gold quality
hypothalamus	UBERON:0001898	38.68	gold quality
nucleus accumbens	UBERON:0001882	38.21	silver quality
muscle layer of sigmoid colon	UBERON:0035805	38.12	silver quality
esophagus mucosa	UBERON:0002469	38.10	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.