DMP1-AS1
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Also known as AC093895.1lnc-SPARCL1-1
Summary
DMP1-AS1 (DMP1 and DSPP antisense RNA 1, HGNC:58144) is a long non-coding RNA gene on chromosome 4q22.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:58144 |
| Approved symbol | DMP1-AS1 |
| Name | DMP1 and DSPP antisense RNA 1 |
| Location | 4q22.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | AC093895.1, lnc-SPARCL1-1 |
| Ensembl gene | ENSG00000249001 |
| Ensembl biotype | lncRNA |
| Entrez | 138842265 |
| RNAcentral | URS000005D191 — lncRNA, 821 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 30 — 30 lncRNA
ENST00000503993, ENST00000506480, ENST00000506814, ENST00000507894, ENST00000701198, ENST00000829286, ENST00000829287, ENST00000829288, ENST00000829289, ENST00000829290, ENST00000829291, ENST00000829292, ENST00000829293, ENST00000829294, ENST00000829295, ENST00000829296, ENST00000829297, ENST00000829298, ENST00000829299, ENST00000829300, ENST00000829301, ENST00000829302, ENST00000829303, ENST00000829304, ENST00000829305, ENST00000829306, ENST00000829307, ENST00000829308, ENST00000829309, ENST00000829310
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000503993 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002027474 | 87682998 | 87683304 |
| ENSE00002056211 | 87730363 | 87730493 |
| ENSE00002061912 | 87733864 | 87733956 |
Expression profiles
Bgee: expression breadth ubiquitous, 108 present calls, max score 82.95.
Top tissues by expression
207 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 82.95 | silver quality |
| sperm | CL:0000019 | 69.60 | silver quality |
| ganglionic eminence | UBERON:0004023 | 61.12 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 59.23 | gold quality |
| right coronary artery | UBERON:0001625 | 58.42 | gold quality |
| right testis | UBERON:0004534 | 57.43 | gold quality |
| left testis | UBERON:0004533 | 56.35 | gold quality |
| gall bladder | UBERON:0002110 | 55.48 | gold quality |
| testis | UBERON:0000473 | 55.41 | gold quality |
| adenohypophysis | UBERON:0002196 | 55.16 | gold quality |
| vermiform appendix | UBERON:0001154 | 54.89 | gold quality |
| thoracic aorta | UBERON:0001515 | 53.82 | gold quality |
| ascending aorta | UBERON:0001496 | 53.59 | gold quality |
| left coronary artery | UBERON:0001626 | 53.47 | gold quality |
| coronary artery | UBERON:0001621 | 53.08 | gold quality |
| right lobe of liver | UBERON:0001114 | 52.88 | gold quality |
| aorta | UBERON:0000947 | 51.76 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 51.74 | gold quality |
| monocyte | CL:0000576 | 51.28 | silver quality |
| left adrenal gland cortex | UBERON:0035825 | 50.78 | gold quality |
| tibial artery | UBERON:0007610 | 50.30 | gold quality |
| islet of Langerhans | UBERON:0000006 | 50.10 | gold quality |
| body of pancreas | UBERON:0001150 | 49.95 | gold quality |
| pancreas | UBERON:0001264 | 49.54 | gold quality |
| nasal cavity mucosa | UBERON:0001826 | 49.20 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 49.04 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 48.98 | gold quality |
| apex of heart | UBERON:0002098 | 48.93 | gold quality |
| muscle of leg | UBERON:0001383 | 48.71 | silver quality |
| lower lobe of lung | UBERON:0008949 | 48.69 | silver quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 3.22 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): autosomal dominant nonsyndromic hearing loss, deafness, autosomal dominant 39, with dentinogenesis imperfecta 1, dentinogenesis imperfecta, dentinogenesis imperfecta type 2, dentinogenesis imperfecta type 3, hereditary optic neuropathy, hypophosphatemic rickets, autosomal recessive, 1