DMXL1-DT

Summary

DMXL1-DT (DMXL1 divergent transcript, HGNC:55568) is a long non-coding RNA gene on chromosome 5q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55568
Approved symbol	DMXL1-DT
Name	DMXL1 divergent transcript
Location	5q23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249494
Ensembl biotype	lncRNA
Entrez	105379143
RNAcentral	URS00002B6301 — lncRNA, 525 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000504820, ENST00000506486, ENST00000510128, ENST00000843246, ENST00000843247

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504820 — 3 exons

Exon	Start	End
ENSE00002040493	119070806	119070902
ENSE00002063676	119007965	119012078
ENSE00002085127	119020077	119020240

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 77.01.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.01	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.11	gold quality
colonic epithelium	UBERON:0000397	68.68	gold quality
bone marrow cell	CL:0002092	65.92	silver quality
skeletal muscle tissue	UBERON:0001134	65.56	gold quality
cortical plate	UBERON:0005343	63.45	gold quality
muscle tissue	UBERON:0002385	63.20	gold quality
ventricular zone	UBERON:0003053	62.20	gold quality
bone marrow	UBERON:0002371	61.97	gold quality
testis	UBERON:0000473	60.43	gold quality
right testis	UBERON:0004534	60.36	gold quality
islet of Langerhans	UBERON:0000006	60.15	gold quality
left testis	UBERON:0004533	59.74	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.53	gold quality
stromal cell of endometrium	CL:0002255	59.33	gold quality
leukocyte	CL:0000738	59.27	gold quality
endometrium	UBERON:0001295	58.81	gold quality
monocyte	CL:0000576	58.64	gold quality
ganglionic eminence	UBERON:0004023	58.28	gold quality
prefrontal cortex	UBERON:0000451	58.04	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.79	gold quality
mucosa of transverse colon	UBERON:0004991	57.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.54	gold quality
right lobe of thyroid gland	UBERON:0001119	57.37	gold quality
kidney	UBERON:0002113	57.29	gold quality
thyroid gland	UBERON:0002046	57.22	gold quality
granulocyte	CL:0000094	57.11	gold quality
duodenum	UBERON:0002114	57.07	gold quality
right adrenal gland cortex	UBERON:0035827	57.04	gold quality
primary visual cortex	UBERON:0002436	56.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.