DNAJC27-AS1

Summary

DNAJC27-AS1 (DNAJC27 antisense RNA 1, HGNC:42943) is a long non-coding RNA gene on chromosome 2p23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42943
Approved symbol	DNAJC27-AS1
Name	DNAJC27 antisense RNA 1
Location	2p23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224165
Ensembl biotype	lncRNA
Entrez	729723
RNAcentral	URS000075C5C5 — lncRNA, 4695 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 36 — 36 lncRNA

ENST00000421842, ENST00000421904, ENST00000422449, ENST00000428614, ENST00000434897, ENST00000445389, ENST00000451291, ENST00000653368, ENST00000657294, ENST00000663498, ENST00000668034, ENST00000687126, ENST00000690413, ENST00000691716, ENST00000702647, ENST00000841448, ENST00000841449, ENST00000841450, ENST00000841451, ENST00000841452, ENST00000841453, ENST00000841454, ENST00000841455, ENST00000841456, ENST00000841457, ENST00000841458, ENST00000841459, ENST00000841460, ENST00000841461, ENST00000841462, ENST00000841463, ENST00000841464, ENST00000841465, ENST00000841466, ENST00000841467, ENST00000841468

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421842 — 2 exons

Exon	Start	End
ENSE00004265844	24972626	24972840
ENSE00004265855	24971360	24972232

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 84.35.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.5895 / max 91.3316, expressed in 1618 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19201	4.3290	1521
19202	1.1410	450
19203	0.1194	52

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	84.35	gold quality
left testis	UBERON:0004533	83.89	gold quality
right testis	UBERON:0004534	83.61	gold quality
bone marrow cell	CL:0002092	82.62	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.73	gold quality
testis	UBERON:0000473	80.05	gold quality
adenohypophysis	UBERON:0002196	79.45	gold quality
hindlimb stylopod muscle	UBERON:0004252	79.45	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	78.73	gold quality
right lobe of thyroid gland	UBERON:0001119	78.44	gold quality
left lobe of thyroid gland	UBERON:0001120	78.41	gold quality
pituitary gland	UBERON:0000007	77.51	gold quality
thyroid gland	UBERON:0002046	77.27	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.00	gold quality
sural nerve	UBERON:0015488	76.55	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	75.83	gold quality
prefrontal cortex	UBERON:0000451	75.68	gold quality
body of pancreas	UBERON:0001150	75.58	gold quality
spinal cord	UBERON:0002240	75.30	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.26	gold quality
islet of Langerhans	UBERON:0000006	75.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	75.05	gold quality
apex of heart	UBERON:0002098	74.97	gold quality
pancreas	UBERON:0001264	74.83	gold quality
cerebellar hemisphere	UBERON:0002245	74.79	gold quality
lower esophagus mucosa	UBERON:0035834	74.79	gold quality
cerebellar cortex	UBERON:0002129	74.76	gold quality
mucosa of transverse colon	UBERON:0004991	74.75	gold quality
metanephros cortex	UBERON:0010533	74.55	gold quality
right atrium auricular region	UBERON:0006631	74.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	5.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.