DNM3-IT1

Summary

DNM3-IT1 (DNM3 intronic transcript 1, HGNC:41494) is a long non-coding RNA gene on chromosome 1q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41494
Approved symbol	DNM3-IT1
Name	DNM3 intronic transcript 1
Location	1q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233540
Ensembl biotype	lncRNA
Entrez	100874284
RNAcentral	URS000081214B — lncRNA, 391 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000450800

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450800 — 2 exons

Exon	Start	End
ENSE00001627054	171864187	171864293
ENSE00001792399	171864399	171864687

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 94.40.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.40	gold quality
corpus callosum	UBERON:0002336	91.00	gold quality
sural nerve	UBERON:0015488	79.55	gold quality
ganglionic eminence	UBERON:0004023	71.59	gold quality
adrenal tissue	UBERON:0018303	68.68	gold quality
right testis	UBERON:0004534	67.90	gold quality
testis	UBERON:0000473	64.66	gold quality
left testis	UBERON:0004533	64.46	gold quality
skeletal muscle tissue	UBERON:0001134	63.79	gold quality
prefrontal cortex	UBERON:0000451	59.84	gold quality
islet of Langerhans	UBERON:0000006	59.22	gold quality
lymph node	UBERON:0000029	58.74	gold quality
monocyte	CL:0000576	57.97	gold quality
vermiform appendix	UBERON:0001154	57.88	gold quality
calcaneal tendon	UBERON:0003701	57.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.36	gold quality
superior frontal gyrus	UBERON:0002661	56.36	gold quality
tonsil	UBERON:0002372	55.48	silver quality
granulocyte	CL:0000094	54.67	gold quality
muscle of leg	UBERON:0001383	54.61	gold quality
primary visual cortex	UBERON:0002436	54.60	gold quality
liver	UBERON:0002107	53.69	gold quality
blood	UBERON:0000178	53.53	gold quality
mucosa of transverse colon	UBERON:0004991	52.73	gold quality
adrenal gland	UBERON:0002369	52.53	gold quality
gastrocnemius	UBERON:0001388	52.46	gold quality
rectum	UBERON:0001052	52.04	gold quality
myometrium	UBERON:0001296	51.11	gold quality
urinary bladder	UBERON:0001255	50.69	gold quality
kidney	UBERON:0002113	50.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.