DNMBP-AS1

Summary

DNMBP-AS1 (DNMBP antisense RNA 1, HGNC:20431) is a long non-coding RNA gene on chromosome 10q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20431
Approved symbol	DNMBP-AS1
Name	DNMBP antisense RNA 1
Location	10q24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ40792, bA287G8.2
Ensembl gene	ENSG00000227695
Ensembl biotype	lncRNA
Entrez	100188954
RNAcentral	URS0000CCE041 — lncRNA, 2655 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000427093, ENST00000434409, ENST00000661150, ENST00000661385

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427093 — 3 exons

Exon	Start	End
ENSE00001740562	99928160	99928240
ENSE00004122293	99927010	99927299
ENSE00004122294	99929736	99930196

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 70.60.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0843 / max 5.3426, expressed in 42 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
205963	0.0843	42

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	70.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.05	gold quality
mucosa of transverse colon	UBERON:0004991	69.98	gold quality
bone marrow cell	CL:0002092	68.12	silver quality
rectum	UBERON:0001052	68.04	gold quality
tonsil	UBERON:0002372	67.99	gold quality
bone marrow	UBERON:0002371	65.67	gold quality
right uterine tube	UBERON:0001302	65.65	gold quality
liver	UBERON:0002107	65.56	gold quality
ganglionic eminence	UBERON:0004023	63.60	gold quality
transverse colon	UBERON:0001157	63.41	gold quality
thyroid gland	UBERON:0002046	62.30	gold quality
left lobe of thyroid gland	UBERON:0001120	62.22	gold quality
ventricular zone	UBERON:0003053	61.81	gold quality
skeletal muscle tissue	UBERON:0001134	61.74	silver quality
cortical plate	UBERON:0005343	61.54	silver quality
duodenum	UBERON:0002114	61.44	gold quality
gall bladder	UBERON:0002110	61.13	gold quality
right lobe of thyroid gland	UBERON:0001119	60.68	gold quality
substantia nigra	UBERON:0002038	60.56	gold quality
right lobe of liver	UBERON:0001114	60.22	gold quality
nucleus accumbens	UBERON:0001882	60.12	gold quality
endometrium	UBERON:0001295	59.88	gold quality
intestine	UBERON:0000160	59.22	gold quality
small intestine	UBERON:0002108	59.20	gold quality
stomach	UBERON:0000945	59.12	gold quality
colon	UBERON:0001155	59.00	gold quality
uterine cervix	UBERON:0000002	58.69	gold quality
saliva-secreting gland	UBERON:0001044	58.67	gold quality
body of stomach	UBERON:0001161	58.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.66

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA DNMBP-AS1 promotes prostate cancer development by regulating LCLAT1. (PMID:36602957)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.