DOCK1-AS1

Summary

DOCK1-AS1 (DOCK1 antisense RNA 1, HGNC:58348) is a long non-coding RNA gene on chromosome 10q26.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58348
Approved symbol	DOCK1-AS1
Name	DOCK1 antisense RNA 1
Location	10q26.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223528
Ensembl biotype	lncRNA
Entrez	105378552

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000432554, ENST00000594559, ENST00000594614, ENST00000595456, ENST00000599979, ENST00000601242, ENST00000601826, ENST00000608350, ENST00000622832, ENST00000627944, ENST00000629917

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432554 — 2 exons

Exon	Start	End
ENSE00001705800	127024770	127025263
ENSE00002986142	127026272	127026507

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 85.80.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.06	gold quality
corpus callosum	UBERON:0002336	79.37	gold quality
colonic epithelium	UBERON:0000397	77.80	gold quality
sural nerve	UBERON:0015488	76.77	gold quality
calcaneal tendon	UBERON:0003701	74.00	gold quality
testis	UBERON:0000473	71.10	gold quality
left testis	UBERON:0004533	70.89	gold quality
right testis	UBERON:0004534	69.65	gold quality
tonsil	UBERON:0002372	67.06	gold quality
skeletal muscle tissue	UBERON:0001134	66.71	gold quality
bone marrow cell	CL:0002092	65.23	silver quality
ventricular zone	UBERON:0003053	63.61	gold quality
muscle tissue	UBERON:0002385	63.46	gold quality
ganglionic eminence	UBERON:0004023	63.32	gold quality
adrenal tissue	UBERON:0018303	61.96	gold quality
bone marrow	UBERON:0002371	61.60	silver quality
urinary bladder	UBERON:0001255	59.39	gold quality
liver	UBERON:0002107	58.94	gold quality
uterine cervix	UBERON:0000002	58.92	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.09	gold quality
cortical plate	UBERON:0005343	57.97	silver quality
lower esophagus mucosa	UBERON:0035834	56.65	gold quality
kidney	UBERON:0002113	56.57	gold quality
thoracic mammary gland	UBERON:0005200	56.32	gold quality
lung	UBERON:0002048	55.56	gold quality
omental fat pad	UBERON:0010414	55.36	gold quality
blood	UBERON:0000178	54.75	gold quality
skin of abdomen	UBERON:0001416	54.65	gold quality
monocyte	CL:0000576	54.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.