DOCK4-AS1

Summary

DOCK4-AS1 (DOCK4 antisense RNA 1, HGNC:40876) is a long non-coding RNA gene on chromosome 7q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40876
Approved symbol	DOCK4-AS1
Name	DOCK4 antisense RNA 1
Location	7q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225572
Ensembl biotype	lncRNA
Entrez	100506413
RNAcentral	URS000075B734 — lncRNA, 2511 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000452714

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452714 — 2 exons

Exon	Start	End
ENSE00001711974	111819378	111821773
ENSE00001753164	111808516	111808613

Expression profiles

Bgee: expression breadth broad, 77 present calls, max score 79.24.

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	79.24	gold quality
colonic epithelium	UBERON:0000397	72.05	gold quality
calcaneal tendon	UBERON:0003701	63.39	gold quality
corpus callosum	UBERON:0002336	62.17	gold quality
left testis	UBERON:0004533	60.28	gold quality
cortical plate	UBERON:0005343	59.89	silver quality
testis	UBERON:0000473	59.18	gold quality
right testis	UBERON:0004534	57.12	gold quality
tendon	UBERON:0000043	54.61	gold quality
right lobe of liver	UBERON:0001114	53.28	gold quality
adrenal tissue	UBERON:0018303	53.08	gold quality
tonsil	UBERON:0002372	52.20	silver quality
adrenal gland	UBERON:0002369	51.03	silver quality
monocyte	CL:0000576	50.41	silver quality
islet of Langerhans	UBERON:0000006	50.01	silver quality
liver	UBERON:0002107	48.03	silver quality
prefrontal cortex	UBERON:0000451	47.64	silver quality
stomach	UBERON:0000945	47.53	silver quality
left adrenal gland	UBERON:0001234	47.12	silver quality
lung	UBERON:0002048	47.07	gold quality
uterine cervix	UBERON:0000002	47.00	silver quality
blood	UBERON:0000178	46.65	silver quality
gastrocnemius	UBERON:0001388	45.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	45.57	silver quality
skeletal muscle tissue	UBERON:0001134	45.35	gold quality
upper lobe of left lung	UBERON:0008952	45.21	gold quality
kidney	UBERON:0002113	44.62	silver quality
upper lobe of lung	UBERON:0008948	44.35	gold quality
left adrenal gland cortex	UBERON:0035825	44.10	silver quality
urinary bladder	UBERON:0001255	44.06	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.