DOCK8-AS1

Summary

DOCK8-AS1 (DOCK8 antisense RNA 1, HGNC:26436) is a long non-coding RNA gene on chromosome 9p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26436
Approved symbol	DOCK8-AS1
Name	DOCK8 antisense RNA 1
Location	9p24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ31158
Ensembl gene	ENSG00000183784
Ensembl biotype	lncRNA
Entrez	157983
RNAcentral	URS0000E60B54 — lncRNA, 2294 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000382387, ENST00000648587

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000382387 — 1 exons

Exon	Start	End
ENSE00003837236	213108	215893

Expression profiles

Bgee: expression breadth ubiquitous, 138 present calls, max score 77.58.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0083 / max 3.3012, expressed in 5 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
99720	0.0083	5

Top tissues by expression

221 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adult mammalian kidney	UBERON:0000082	77.58	gold quality
kidney	UBERON:0002113	76.23	gold quality
cortex of kidney	UBERON:0001225	70.83	gold quality
monocyte	CL:0000576	69.59	gold quality
leukocyte	CL:0000738	69.09	gold quality
bone marrow cell	CL:0002092	68.08	silver quality
adult organism	UBERON:0007023	67.24	gold quality
renal medulla	UBERON:0000362	64.72	gold quality
palpebral conjunctiva	UBERON:0001812	64.42	gold quality
blood	UBERON:0000178	63.83	gold quality
bronchial epithelial cell	CL:0002328	63.56	gold quality
bone marrow	UBERON:0002371	62.99	gold quality
bronchus	UBERON:0002185	62.51	gold quality
left adrenal gland cortex	UBERON:0035825	61.56	gold quality
left adrenal gland	UBERON:0001234	61.40	gold quality
right adrenal gland cortex	UBERON:0035827	61.00	gold quality
granulocyte	CL:0000094	60.70	gold quality
right adrenal gland	UBERON:0001233	60.65	gold quality
adrenal gland	UBERON:0002369	60.50	gold quality
placenta	UBERON:0001987	60.08	gold quality
adrenal cortex	UBERON:0001235	59.96	gold quality
adrenal tissue	UBERON:0018303	59.16	gold quality
metanephros cortex	UBERON:0010533	56.97	gold quality
mammary duct	UBERON:0001765	56.72	gold quality
lower esophagus muscularis layer	UBERON:0035833	56.38	gold quality
lower esophagus	UBERON:0013473	56.37	gold quality
nasal cavity epithelium	UBERON:0005384	56.34	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.61	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.50	gold quality
decidua	UBERON:0002450	55.15	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	7.59
E-ANND-3	yes	5.37

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.