DOCK8-AS2

Summary

DOCK8-AS2 (DOCK8 antisense RNA 2, HGNC:55822) is a long non-coding RNA gene on chromosome 9p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55822
Approved symbol	DOCK8-AS2
Name	DOCK8 antisense RNA 2
Location	9p24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227155
Ensembl biotype	lncRNA
Entrez	112268042
RNAcentral	URS0000811C8E — lncRNA, 1351 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000415004, ENST00000585631, ENST00000585819, ENST00000585944, ENST00000586805, ENST00000588474, ENST00000588989, ENST00000589287, ENST00000589387, ENST00000590240, ENST00000590518, ENST00000591577, ENST00000592805, ENST00000593137, ENST00000608617, ENST00000628764, ENST00000813016

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415004 — 4 exons

Exon	Start	End
ENSE00001609856	456201	456703
ENSE00001650523	454304	454606
ENSE00002738368	492084	492248
ENSE00002935861	488957	489066

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 89.03.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	89.03	gold quality
bone marrow	UBERON:0002371	86.60	gold quality
monocyte	CL:0000576	85.86	gold quality
leukocyte	CL:0000738	84.55	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.30	gold quality
blood	UBERON:0000178	81.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.63	gold quality
sural nerve	UBERON:0015488	72.55	gold quality
lymph node	UBERON:0000029	72.15	gold quality
spleen	UBERON:0002106	71.30	gold quality
colonic epithelium	UBERON:0000397	70.96	gold quality
tonsil	UBERON:0002372	70.00	gold quality
corpus callosum	UBERON:0002336	69.80	gold quality
right lung	UBERON:0002167	68.84	gold quality
right uterine tube	UBERON:0001302	68.66	gold quality
upper lobe of left lung	UBERON:0008952	68.04	gold quality
right testis	UBERON:0004534	67.12	gold quality
lung	UBERON:0002048	67.08	gold quality
vermiform appendix	UBERON:0001154	66.79	gold quality
right adrenal gland cortex	UBERON:0035827	66.72	gold quality
granulocyte	CL:0000094	66.30	gold quality
ganglionic eminence	UBERON:0004023	66.25	gold quality
testis	UBERON:0000473	66.00	gold quality
gall bladder	UBERON:0002110	65.63	gold quality
left testis	UBERON:0004533	65.59	gold quality
rectum	UBERON:0001052	65.55	gold quality
small intestine Peyer’s patch	UBERON:0003454	65.42	gold quality
right adrenal gland	UBERON:0001233	65.34	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.34	gold quality
adrenal tissue	UBERON:0018303	65.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.34

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.