DPP3-DT

Summary

DPP3-DT (DPP3 divergent transcript, HGNC:55494) is a long non-coding RNA gene on chromosome 11q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55494
Approved symbol	DPP3-DT
Name	DPP3 divergent transcript
Location	11q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255517
Ensembl biotype	lncRNA
Entrez	101928069
RNAcentral	URS000075E539 — lncRNA, 846 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000525142, ENST00000527092, ENST00000527274, ENST00000533502, ENST00000602951, ENST00000690327, ENST00000691379, ENST00000693584, ENST00000702177, ENST00000736419

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525142 — 2 exons

Exon	Start	End
ENSE00004069745	66480039	66480301
ENSE00004069749	66477344	66478091

Expression profiles

Bgee: expression breadth ubiquitous, 167 present calls, max score 86.70.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.3971 / max 75.1101, expressed in 1762 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
120809	7.3971	1762

Top tissues by expression

255 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.70	gold quality
sperm	CL:0000019	85.86	silver quality
kidney epithelium	UBERON:0004819	85.64	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.44	gold quality
upper arm skin	UBERON:0004263	84.99	gold quality
pancreatic ductal cell	CL:0002079	83.30	silver quality
tibialis anterior	UBERON:0001385	82.79	silver quality
left testis	UBERON:0004533	81.28	gold quality
right testis	UBERON:0004534	80.18	gold quality
deltoid	UBERON:0001476	79.80	gold quality
left ventricle myocardium	UBERON:0006566	78.96	gold quality
ileal mucosa	UBERON:0000331	78.78	silver quality
testis	UBERON:0000473	78.74	gold quality
cardiac muscle of right atrium	UBERON:0003379	78.70	gold quality
myocardium	UBERON:0002349	77.72	gold quality
nasal cavity epithelium	UBERON:0005384	77.62	gold quality
cerebellar vermis	UBERON:0004720	77.41	gold quality
epithelial cell of pancreas	CL:0000083	77.01	gold quality
mucosa of transverse colon	UBERON:0004991	76.72	gold quality
body of pancreas	UBERON:0001150	76.44	gold quality
metanephros cortex	UBERON:0010533	76.01	gold quality
monocyte	CL:0000576	75.82	gold quality
pancreas	UBERON:0001264	75.73	gold quality
stromal cell of endometrium	CL:0002255	75.62	gold quality
right uterine tube	UBERON:0001302	75.55	gold quality
leukocyte	CL:0000738	75.46	gold quality
gastrocnemius	UBERON:0001388	75.40	gold quality
endothelial cell	CL:0000115	75.17	gold quality
muscle tissue	UBERON:0002385	74.99	gold quality
muscle of leg	UBERON:0001383	74.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.01

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.