DPP4-DT

Summary

DPP4-DT (DPP4 divergent transcript, HGNC:40191) is a long non-coding RNA gene on chromosome 2q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40191
Approved symbol	DPP4-DT
Name	DPP4 divergent transcript
Location	2q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230918
Ensembl biotype	lncRNA
Entrez	100131604
RNAcentral	URS0000BC43FF — lncRNA, 916 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000418335, ENST00000670014, ENST00000693081, ENST00000839446, ENST00000839447, ENST00000839448, ENST00000839449, ENST00000839450

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418335 — 3 exons

Exon	Start	End
ENSE00001633541	162073412	162073583
ENSE00001683039	162073256	162073337
ENSE00001745348	162074784	162075169

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 83.27.

FANTOM5 (CAGE): breadth broad, TPM avg 0.3793 / max 37.8026, expressed in 202 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
23373	0.2440	123
23372	0.1275	58
23371	0.0078	2

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	83.27	gold quality
prostate gland	UBERON:0002367	78.85	gold quality
placenta	UBERON:0001987	75.73	gold quality
spleen	UBERON:0002106	73.37	gold quality
apex of heart	UBERON:0002098	69.57	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.50	gold quality
adipose tissue	UBERON:0001013	68.89	gold quality
omental fat pad	UBERON:0010414	68.28	gold quality
tonsil	UBERON:0002372	67.44	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.33	gold quality
granulocyte	CL:0000094	65.80	gold quality
islet of Langerhans	UBERON:0000006	65.57	gold quality
heart left ventricle	UBERON:0002084	65.22	gold quality
tibial nerve	UBERON:0001323	64.91	gold quality
stromal cell of endometrium	CL:0002255	63.82	gold quality
skeletal muscle tissue	UBERON:0001134	63.59	gold quality
thoracic mammary gland	UBERON:0005200	63.49	gold quality
primary visual cortex	UBERON:0002436	63.25	gold quality
vermiform appendix	UBERON:0001154	62.57	gold quality
sural nerve	UBERON:0015488	62.52	silver quality
left adrenal gland	UBERON:0001234	62.49	gold quality
rectum	UBERON:0001052	62.46	gold quality
gall bladder	UBERON:0002110	62.45	gold quality
adrenal gland	UBERON:0002369	61.71	gold quality
right adrenal gland	UBERON:0001233	61.21	gold quality
left adrenal gland cortex	UBERON:0035825	61.21	gold quality
saliva-secreting gland	UBERON:0001044	60.78	gold quality
prefrontal cortex	UBERON:0000451	60.50	gold quality
lymph node	UBERON:0000029	60.24	gold quality
pancreas	UBERON:0001264	60.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.