DPYD-AS1

Summary

DPYD-AS1 (DPYD antisense RNA 1, HGNC:40195) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40195
Approved symbol	DPYD-AS1
Name	DPYD antisense RNA 1
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232878
Ensembl biotype	lncRNA
Entrez	100873932
RNAcentral	URS000075AC5D — lncRNA, 548 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000422980, ENST00000629811, ENST00000630798

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422980 — 5 exons

Exon	Start	End
ENSE00001637442	97322707	97322955
ENSE00001654683	97308390	97308424
ENSE00001660206	97265414	97265477
ENSE00001703967	97095923	97095986
ENSE00001725857	97306189	97306309

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 82.17.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	82.17	gold quality
corpus callosum	UBERON:0002336	81.83	gold quality
colonic epithelium	UBERON:0000397	80.28	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.53	gold quality
calcaneal tendon	UBERON:0003701	77.54	gold quality
bone marrow cell	CL:0002092	74.81	gold quality
skeletal muscle tissue	UBERON:0001134	70.03	silver quality
monocyte	CL:0000576	68.12	gold quality
bone marrow	UBERON:0002371	66.93	gold quality
blood	UBERON:0000178	66.45	gold quality
liver	UBERON:0002107	63.93	gold quality
tonsil	UBERON:0002372	62.40	gold quality
endometrium	UBERON:0001295	61.97	gold quality
smooth muscle tissue	UBERON:0001135	61.12	gold quality
superior frontal gyrus	UBERON:0002661	61.09	gold quality
tibial nerve	UBERON:0001323	59.75	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.13	gold quality
lymph node	UBERON:0000029	59.06	gold quality
stromal cell of endometrium	CL:0002255	56.66	gold quality
urinary bladder	UBERON:0001255	56.60	gold quality
lung	UBERON:0002048	55.69	gold quality
kidney	UBERON:0002113	55.60	gold quality
mucosa of stomach	UBERON:0001199	54.86	gold quality
duodenum	UBERON:0002114	54.26	gold quality
prefrontal cortex	UBERON:0000451	54.10	gold quality
right lobe of liver	UBERON:0001114	53.58	gold quality
vermiform appendix	UBERON:0001154	53.06	gold quality
placenta	UBERON:0001987	52.59	gold quality
omental fat pad	UBERON:0010414	52.57	gold quality
uterine cervix	UBERON:0000002	52.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.