DPYD-AS2

Summary

DPYD-AS2 (DPYD antisense RNA 2, HGNC:40196) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40196
Approved symbol	DPYD-AS2
Name	DPYD antisense RNA 2
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235777
Ensembl biotype	lncRNA
Entrez	100873933
RNAcentral	URS000075A138 — lncRNA, 817 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000422259, ENST00000431362

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422259 — 3 exons

Exon	Start	End
ENSE00001597495	97796965	97797072
ENSE00001670338	97797468	97798066
ENSE00001735234	97797215	97797295

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 88.12.

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.12	gold quality
colonic epithelium	UBERON:0000397	80.60	gold quality
bone marrow cell	CL:0002092	77.26	gold quality
corpus callosum	UBERON:0002336	71.69	gold quality
skeletal muscle tissue	UBERON:0001134	66.68	silver quality
bone marrow	UBERON:0002371	66.66	gold quality
monocyte	CL:0000576	64.87	gold quality
tonsil	UBERON:0002372	63.35	silver quality
liver	UBERON:0002107	62.72	gold quality
calcaneal tendon	UBERON:0003701	61.75	gold quality
blood	UBERON:0000178	61.17	gold quality
ganglionic eminence	UBERON:0004023	60.48	gold quality
urinary bladder	UBERON:0001255	56.86	gold quality
gall bladder	UBERON:0002110	55.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.01	gold quality
stomach	UBERON:0000945	53.16	gold quality
adrenal tissue	UBERON:0018303	51.98	gold quality
lymph node	UBERON:0000029	51.94	gold quality
kidney	UBERON:0002113	51.91	silver quality
thoracic mammary gland	UBERON:0005200	51.66	gold quality
cortex of kidney	UBERON:0001225	51.20	silver quality
islet of Langerhans	UBERON:0000006	50.72	gold quality
adrenal gland	UBERON:0002369	50.19	silver quality
lung	UBERON:0002048	50.08	gold quality
multicellular organism	UBERON:0000468	49.98	gold quality
testis	UBERON:0000473	49.48	gold quality
muscle of leg	UBERON:0001383	49.45	gold quality
intestine	UBERON:0000160	49.28	gold quality
left testis	UBERON:0004533	48.88	gold quality
colon	UBERON:0001155	48.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.