DPYD-IT1

Summary

DPYD-IT1 (DPYD intronic transcript 1, HGNC:41326) is a long non-coding RNA gene on chromosome 1p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41326
Approved symbol	DPYD-IT1
Name	DPYD intronic transcript 1
Location	1p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232542
Ensembl biotype	lncRNA
Entrez	100874267
RNAcentral	URS00001B87E6 — lncRNA, 401 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424982 — 2 exons

Exon	Start	End
ENSE00001688988	97394154	97394419
ENSE00001789359	97420007	97420141

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 86.99.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.99	gold quality
corpus callosum	UBERON:0002336	76.80	gold quality
tonsil	UBERON:0002372	73.15	gold quality
bone marrow cell	CL:0002092	71.28	gold quality
cortical plate	UBERON:0005343	68.86	gold quality
skeletal muscle tissue	UBERON:0001134	68.61	gold quality
sural nerve	UBERON:0015488	66.87	gold quality
monocyte	CL:0000576	66.74	gold quality
leukocyte	CL:0000738	66.16	gold quality
ganglionic eminence	UBERON:0004023	65.97	gold quality
bone marrow	UBERON:0002371	65.43	gold quality
testis	UBERON:0000473	64.34	gold quality
blood	UBERON:0000178	63.74	gold quality
urinary bladder	UBERON:0001255	59.23	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.31	gold quality
liver	UBERON:0002107	57.97	gold quality
calcaneal tendon	UBERON:0003701	57.60	gold quality
superior frontal gyrus	UBERON:0002661	57.34	gold quality
rectum	UBERON:0001052	55.76	gold quality
islet of Langerhans	UBERON:0000006	54.09	gold quality
cortex of kidney	UBERON:0001225	53.95	gold quality
granulocyte	CL:0000094	53.94	gold quality
lower esophagus mucosa	UBERON:0035834	53.59	gold quality
right lobe of liver	UBERON:0001114	53.08	gold quality
metanephros cortex	UBERON:0010533	53.08	gold quality
kidney	UBERON:0002113	52.94	gold quality
vermiform appendix	UBERON:0001154	52.85	gold quality
gastrocnemius	UBERON:0001388	52.78	gold quality
prefrontal cortex	UBERON:0000451	52.34	gold quality
pancreas	UBERON:0001264	51.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.54

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.