DRAM1-AS1

Summary

DRAM1-AS1 (DRAM1 antisense RNA 1, HGNC:53335) is a long non-coding RNA gene on chromosome 12q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53335
Approved symbol	DRAM1-AS1
Name	DRAM1 antisense RNA 1
Location	12q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258308
Ensembl biotype	lncRNA
Entrez	107984548
RNAcentral	URS0002A28BFB — lncRNA, 1193 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000547004, ENST00000550307, ENST00000655973, ENST00000845155

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000547004 — 3 exons

Exon	Start	End
ENSE00002326621	101957213	101957401
ENSE00002369834	101961030	101961122
ENSE00002419552	101962250	101962390

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 72.42.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	72.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.20	gold quality
ventricular zone	UBERON:0003053	60.56	gold quality
left testis	UBERON:0004533	58.94	gold quality
ganglionic eminence	UBERON:0004023	57.94	gold quality
testis	UBERON:0000473	57.88	gold quality
right testis	UBERON:0004534	57.51	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.00	gold quality
cortical plate	UBERON:0005343	55.81	silver quality
vermiform appendix	UBERON:0001154	54.64	gold quality
monocyte	CL:0000576	54.24	gold quality
placenta	UBERON:0001987	53.96	gold quality
primary visual cortex	UBERON:0002436	53.65	gold quality
blood	UBERON:0000178	52.83	gold quality
smooth muscle tissue	UBERON:0001135	52.17	gold quality
prefrontal cortex	UBERON:0000451	51.93	gold quality
rectum	UBERON:0001052	51.77	gold quality
mucosa of stomach	UBERON:0001199	50.58	gold quality
islet of Langerhans	UBERON:0000006	50.53	gold quality
muscle of leg	UBERON:0001383	50.41	gold quality
gall bladder	UBERON:0002110	50.26	gold quality
endocervix	UBERON:0000458	49.70	gold quality
endometrium	UBERON:0001295	49.69	silver quality
gastrocnemius	UBERON:0001388	49.30	gold quality
urinary bladder	UBERON:0001255	49.10	gold quality
lymph node	UBERON:0000029	49.03	gold quality
body of pancreas	UBERON:0001150	48.68	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.45	gold quality
superior frontal gyrus	UBERON:0002661	46.97	silver quality
frontal cortex	UBERON:0001870	46.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.