DSCAM-IT1

Summary

DSCAM-IT1 (DSCAM intronic transcript 1, HGNC:41327) is a long non-coding RNA gene on chromosome 21q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41327
Approved symbol	DSCAM-IT1
Name	DSCAM intronic transcript 1
Location	21q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233756
Ensembl biotype	lncRNA
Entrez	100874326
RNAcentral	URS000075E66D — lncRNA, 720 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000440363, ENST00000441910

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440363 — 4 exons

Exon	Start	End
ENSE00001636286	40629540	40629641
ENSE00001687067	40618507	40618868
ENSE00001753303	40621255	40621400
ENSE00001764323	40630658	40630767

Expression profiles

Bgee: expression breadth broad, 50 present calls, max score 86.06.

Top tissues by expression

50 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.06	gold quality
corpus callosum	UBERON:0002336	79.01	gold quality
cortical plate	UBERON:0005343	63.92	gold quality
liver	UBERON:0002107	58.83	gold quality
superior frontal gyrus	UBERON:0002661	56.02	gold quality
islet of Langerhans	UBERON:0000006	54.86	gold quality
prefrontal cortex	UBERON:0000451	53.75	gold quality
primary visual cortex	UBERON:0002436	53.25	gold quality
colon	UBERON:0001155	52.64	silver quality
intestine	UBERON:0000160	52.55	silver quality
monocyte	CL:0000576	52.41	gold quality
blood	UBERON:0000178	51.17	gold quality
placenta	UBERON:0001987	50.43	silver quality
stomach	UBERON:0000945	50.06	gold quality
lung	UBERON:0002048	48.75	gold quality
skin of abdomen	UBERON:0001416	48.46	gold quality
thyroid gland	UBERON:0002046	47.64	gold quality
cerebellum	UBERON:0002037	47.49	silver quality
cerebellar cortex	UBERON:0002129	47.19	silver quality
frontal cortex	UBERON:0001870	46.26	gold quality
cerebellar hemisphere	UBERON:0002245	46.22	gold quality
adenohypophysis	UBERON:0002196	45.32	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.31	gold quality
amygdala	UBERON:0001876	45.24	gold quality
cerebral cortex	UBERON:0000956	45.20	gold quality
brain	UBERON:0000955	44.98	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	44.61	gold quality
multicellular organism	UBERON:0000468	44.28	gold quality
Ammon’s horn	UBERON:0001954	44.19	gold quality
putamen	UBERON:0001874	44.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.