DSCAS

Summary

DSCAS (DSC1/DSC2 antisense RNA, HGNC:51116) is a long non-coding RNA gene on chromosome 18q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51116
Approved symbol	DSCAS
Name	DSC1/DSC2 antisense RNA
Location	18q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000265888
Ensembl biotype	lncRNA
Entrez	101927698
RNAcentral	URS000051761A — lncRNA, 553 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000581836, ENST00000654403, ENST00000715887, ENST00000715888

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581836 — 4 exons

Exon	Start	End
ENSE00002717509	31150799	31150888
ENSE00002734002	31103123	31103194
ENSE00003982720	31162535	31163414
ENSE00004028246	31101572	31101723

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 91.02.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5647 / max 59.8277, expressed in 453 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
169807	1.2789	290
169808	0.2858	151

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.02	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.40	gold quality
skin of leg	UBERON:0001511	77.57	gold quality
zone of skin	UBERON:0000014	77.19	gold quality
skin of abdomen	UBERON:0001416	76.39	gold quality
heart left ventricle	UBERON:0002084	70.22	gold quality
right atrium auricular region	UBERON:0006631	67.87	gold quality
heart	UBERON:0000948	67.26	gold quality
right uterine tube	UBERON:0001302	66.28	gold quality
apex of heart	UBERON:0002098	65.39	gold quality
nucleus accumbens	UBERON:0001882	65.05	gold quality
caudate nucleus	UBERON:0001873	63.05	gold quality
putamen	UBERON:0001874	62.94	gold quality
amygdala	UBERON:0001876	61.16	gold quality
temporal lobe	UBERON:0001871	61.14	gold quality
anterior cingulate cortex	UBERON:0009835	60.64	gold quality
duodenum	UBERON:0002114	60.30	gold quality
substantia nigra	UBERON:0002038	60.16	gold quality
sural nerve	UBERON:0015488	59.38	silver quality
islet of Langerhans	UBERON:0000006	58.42	gold quality
brain	UBERON:0000955	58.31	gold quality
cerebral cortex	UBERON:0000956	57.98	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	57.95	gold quality
liver	UBERON:0002107	57.67	gold quality
right frontal lobe	UBERON:0002810	57.62	gold quality
prefrontal cortex	UBERON:0000451	57.44	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.42	gold quality
Ammon’s horn	UBERON:0001954	57.41	gold quality
frontal cortex	UBERON:0001870	57.24	gold quality
blood	UBERON:0000178	56.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.