DSCR10

Summary

DSCR10 (Down syndrome critical region 10, HGNC:16302) is a long non-coding RNA gene on chromosome 21q22.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16302
Approved symbol	DSCR10
Name	Down syndrome critical region 10
Location	21q22.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233316
Ensembl biotype	lncRNA
Entrez	259234
RNAcentral	URS000018E2F9 — lncRNA, 860 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000432141

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432141 — 3 exons

Exon	Start	End
ENSE00001599007	38208135	38208644
ENSE00001675372	38206156	38206360
ENSE00001748556	38206472	38206616

Expression profiles

Bgee: expression breadth broad, 24 present calls, max score 83.40.

Top tissues by expression

154 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	83.40	gold quality
cerebellar vermis	UBERON:0004720	78.81	silver quality
endothelial cell	CL:0000115	78.28	silver quality
mammary duct	UBERON:0001765	77.99	gold quality
cerebellar hemisphere	UBERON:0002245	77.99	silver quality
vena cava	UBERON:0004087	77.09	gold quality
caecum	UBERON:0001153	76.41	gold quality
coronary artery	UBERON:0001621	76.34	gold quality
body of tongue	UBERON:0011876	76.09	gold quality
metanephros	UBERON:0000081	75.82	gold quality
subthalamic nucleus	UBERON:0001906	75.71	gold quality
thymus	UBERON:0002370	75.63	silver quality
oocyte	CL:0000023	75.50	gold quality
tongue	UBERON:0001723	75.41	gold quality
pharyngeal mucosa	UBERON:0000355	75.40	gold quality
nucleus accumbens	UBERON:0001882	75.22	gold quality
ventral tegmental area	UBERON:0002691	74.91	gold quality
bone marrow	UBERON:0002371	74.74	gold quality
superior surface of tongue	UBERON:0007371	74.72	gold quality
dorsal plus ventral thalamus	UBERON:0001897	74.69	gold quality
corpus callosum	UBERON:0002336	74.50	gold quality
inferior vagus X ganglion	UBERON:0005363	74.47	gold quality
cardia of stomach	UBERON:0001162	74.45	gold quality
nasal cavity mucosa	UBERON:0001826	74.26	gold quality
pericardium	UBERON:0002407	74.18	gold quality
substantia nigra pars reticulata	UBERON:0001966	74.10	gold quality
saphenous vein	UBERON:0007318	74.09	gold quality
nasal cavity epithelium	UBERON:0005384	74.05	gold quality
lateral globus pallidus	UBERON:0002476	74.03	gold quality
trachea	UBERON:0003126	73.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.