DSCR4-IT1

Summary

DSCR4-IT1 (DSCR4 intronic transcript 1, HGNC:41328) is a long non-coding RNA gene on chromosome 21q22.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41328
Approved symbol	DSCR4-IT1
Name	DSCR4 intronic transcript 1
Location	21q22.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223608
Ensembl biotype	lncRNA
Entrez	100874327
RNAcentral	URS00003EFE4C — lncRNA, 424 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000417138

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417138 — 2 exons

Exon	Start	End
ENSE00001610692	38006544	38006826
ENSE00001763784	38010478	38010618

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 83.50.

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.82	gold quality
placenta	UBERON:0001987	65.64	gold quality
monocyte	CL:0000576	62.73	gold quality
blood	UBERON:0000178	56.22	gold quality
islet of Langerhans	UBERON:0000006	53.63	gold quality
muscle of leg	UBERON:0001383	51.81	gold quality
gastrocnemius	UBERON:0001388	51.24	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.54	gold quality
body of pancreas	UBERON:0001150	47.90	gold quality
heart left ventricle	UBERON:0002084	47.79	gold quality
right atrium auricular region	UBERON:0006631	47.01	gold quality
skin of leg	UBERON:0001511	46.87	gold quality
hypothalamus	UBERON:0001898	46.35	gold quality
esophagus mucosa	UBERON:0002469	46.28	gold quality
left ovary	UBERON:0002119	45.68	gold quality
lower esophagus	UBERON:0013473	45.15	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.05	gold quality
tibial artery	UBERON:0007610	43.84	silver quality
adult mammalian kidney	UBERON:0000082	43.77	silver quality
anterior cingulate cortex	UBERON:0009835	43.64	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.62	silver quality
Ammon’s horn	UBERON:0001954	43.04	silver quality
omental fat pad	UBERON:0010414	42.93	gold quality
left lobe of thyroid gland	UBERON:0001120	42.61	gold quality
right adrenal gland	UBERON:0001233	42.55	gold quality
transverse colon	UBERON:0001157	42.53	gold quality
skin of abdomen	UBERON:0001416	41.93	gold quality
lung	UBERON:0002048	41.86	gold quality
left adrenal gland cortex	UBERON:0035825	41.79	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.