DSG1-AS1

Summary

DSG1-AS1 (DSG1 antisense RNA 1, HGNC:51115) is a long non-coding RNA gene on chromosome 18q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51115
Approved symbol	DSG1-AS1
Name	DSG1 antisense RNA 1
Location	18q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266729
Ensembl biotype	lncRNA
Entrez	101927718
RNAcentral	URS000075C999 — lncRNA, 730 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000578119, ENST00000578477, ENST00000581452, ENST00000581856, ENST00000812429, ENST00000812430, ENST00000812431

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578119 — 3 exons

Exon	Start	End
ENSE00002688280	31343384	31343698
ENSE00002711861	31347720	31347820
ENSE00002729775	31353900	31353936

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 91.07.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0508 / max 24.6333, expressed in 14 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
171571	0.0212	9
171572	0.0181	11
171569	0.0075	3
171570	0.0039	3

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.07	silver quality
esophagus mucosa	UBERON:0002469	90.12	gold quality
lower esophagus mucosa	UBERON:0035834	88.67	gold quality
esophagus	UBERON:0001043	83.97	gold quality
vagina	UBERON:0000996	80.66	gold quality
tonsil	UBERON:0002372	77.10	gold quality
left testis	UBERON:0004533	75.00	gold quality
testis	UBERON:0000473	74.28	gold quality
skin of abdomen	UBERON:0001416	73.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.07	gold quality
zone of skin	UBERON:0000014	72.97	gold quality
skin of leg	UBERON:0001511	72.25	gold quality
ectocervix	UBERON:0012249	72.25	gold quality
right testis	UBERON:0004534	71.92	gold quality
uterine cervix	UBERON:0000002	67.85	gold quality
multicellular organism	UBERON:0000468	64.86	gold quality
colonic epithelium	UBERON:0000397	62.79	silver quality
stromal cell of endometrium	CL:0002255	62.56	gold quality
minor salivary gland	UBERON:0001830	61.94	gold quality
left ovary	UBERON:0002119	59.04	gold quality
ovary	UBERON:0000992	57.28	gold quality
vermiform appendix	UBERON:0001154	56.21	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.86	gold quality
islet of Langerhans	UBERON:0000006	55.40	gold quality
liver	UBERON:0002107	55.20	silver quality
superior frontal gyrus	UBERON:0002661	53.95	gold quality
blood	UBERON:0000178	53.52	gold quality
smooth muscle tissue	UBERON:0001135	52.59	gold quality
prefrontal cortex	UBERON:0000451	52.50	gold quality
monocyte	CL:0000576	51.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.