DSG2-AS1

Summary

DSG2-AS1 (DSG2 antisense RNA 1, HGNC:51311) is a long non-coding RNA gene on chromosome 18q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51311
Approved symbol	DSG2-AS1
Name	DSG2 antisense RNA 1
Location	18q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264859
Ensembl biotype	lncRNA
Entrez	100652770
RNAcentral	URS000075E03B — lncRNA, 2000 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000579251, ENST00000583706, ENST00000657343, ENST00000664179, ENST00000812971

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000579251 — 4 exons

Exon	Start	End
ENSE00002686655	31555963	31556121
ENSE00002688691	31554642	31554715
ENSE00002701703	31556557	31556905
ENSE00002724297	31550132	31550359

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 97.02.

Top tissues by expression

207 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oocyte	CL:0000023	97.02	gold quality
buccal mucosa cell	CL:0002336	96.29	gold quality
sperm	CL:0000019	95.01	gold quality
secondary oocyte	CL:0000655	93.98	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.75	gold quality
endothelial cell	CL:0000115	80.38	gold quality
mucosa of transverse colon	UBERON:0004991	67.65	gold quality
lower lobe of lung	UBERON:0008949	67.09	gold quality
rectum	UBERON:0001052	63.09	gold quality
duodenum	UBERON:0002114	62.75	gold quality
transverse colon	UBERON:0001157	62.72	gold quality
amniotic fluid	UBERON:0000173	62.30	silver quality
testis	UBERON:0000473	60.58	gold quality
left testis	UBERON:0004533	60.46	gold quality
sural nerve	UBERON:0015488	59.53	silver quality
right testis	UBERON:0004534	59.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.07	gold quality
ventricular zone	UBERON:0003053	58.09	silver quality
body of stomach	UBERON:0001161	58.05	gold quality
jejunal mucosa	UBERON:0000399	57.84	gold quality
islet of Langerhans	UBERON:0000006	57.60	gold quality
upper leg skin	UBERON:0004262	57.45	gold quality
right lobe of liver	UBERON:0001114	56.99	gold quality
epithelium of nasopharynx	UBERON:0001951	56.83	gold quality
colon	UBERON:0001155	56.59	gold quality
large intestine	UBERON:0000059	55.91	gold quality
stomach	UBERON:0000945	55.75	gold quality
intestine	UBERON:0000160	55.73	gold quality
skin of hip	UBERON:0001554	55.63	silver quality
small intestine	UBERON:0002108	55.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.