DST-AS1
gene geneOn this page
Summary
DST-AS1 (DST antisense RNA 1, HGNC:40098) is a long non-coding RNA gene on chromosome 6p12.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40098 |
| Approved symbol | DST-AS1 |
| Name | DST antisense RNA 1 |
| Location | 6p12.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000231441 |
| Ensembl biotype | lncRNA |
| Entrez | 101930010 |
| RNAcentral | URS00007E4B2E — lncRNA, 843 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 4 — 4 lncRNA
ENST00000426453, ENST00000662493, ENST00000836485, ENST00000836486
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000426453 — 4 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001624381 | 56844002 | 56844066 |
| ENSE00001688046 | 56861828 | 56861915 |
| ENSE00001688817 | 56863071 | 56863244 |
| ENSE00001800173 | 56863855 | 56864078 |
Expression profiles
Bgee: expression breadth ubiquitous, 115 present calls, max score 87.22.
Top tissues by expression
115 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 87.22 | silver quality |
| cortical plate | UBERON:0005343 | 68.60 | gold quality |
| ventricular zone | UBERON:0003053 | 68.02 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 66.85 | gold quality |
| apex of heart | UBERON:0002098 | 65.87 | gold quality |
| ganglionic eminence | UBERON:0004023 | 64.58 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 62.51 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 62.36 | gold quality |
| islet of Langerhans | UBERON:0000006 | 60.01 | gold quality |
| gall bladder | UBERON:0002110 | 58.89 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 58.88 | gold quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 57.56 | gold quality |
| muscle of leg | UBERON:0001383 | 56.13 | gold quality |
| prefrontal cortex | UBERON:0000451 | 55.99 | gold quality |
| gastrocnemius | UBERON:0001388 | 55.62 | gold quality |
| substantia nigra | UBERON:0002038 | 55.51 | gold quality |
| placenta | UBERON:0001987 | 55.10 | gold quality |
| right testis | UBERON:0004534 | 54.39 | gold quality |
| heart left ventricle | UBERON:0002084 | 54.21 | gold quality |
| left testis | UBERON:0004533 | 54.07 | gold quality |
| testis | UBERON:0000473 | 53.86 | gold quality |
| tibial nerve | UBERON:0001323 | 53.82 | gold quality |
| pituitary gland | UBERON:0000007 | 53.46 | gold quality |
| right coronary artery | UBERON:0001625 | 53.37 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 53.32 | gold quality |
| heart | UBERON:0000948 | 53.05 | gold quality |
| amygdala | UBERON:0001876 | 53.01 | gold quality |
| blood | UBERON:0000178 | 52.95 | gold quality |
| stromal cell of endometrium | CL:0002255 | 52.92 | silver quality |
| adenohypophysis | UBERON:0002196 | 52.47 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.63 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): hereditary sensory and autonomic neuropathy type 6