DTHD1-AS1

Summary

DTHD1-AS1 (DTHD1 antisense RNA 1, HGNC:58756) is a long non-coding RNA gene on chromosome 4p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58756
Approved symbol	DTHD1-AS1
Name	DTHD1 antisense RNA 1
Location	4p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251438
Ensembl biotype	lncRNA
Entrez	143528979

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000504344, ENST00000812646

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504344 — 3 exons

Exon	Start	End
ENSE00002038682	36311190	36311313
ENSE00002072492	36392081	36392410
ENSE00002082703	36311693	36311779

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 78.32.

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.32	silver quality
monocyte	CL:0000576	59.33	gold quality
sural nerve	UBERON:0015488	58.77	silver quality
islet of Langerhans	UBERON:0000006	58.26	gold quality
cortex of kidney	UBERON:0001225	56.09	gold quality
endometrium	UBERON:0001295	55.49	silver quality
granulocyte	CL:0000094	54.42	gold quality
bone marrow	UBERON:0002371	54.08	gold quality
blood	UBERON:0000178	52.90	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	51.37	gold quality
lymph node	UBERON:0000029	50.69	silver quality
prefrontal cortex	UBERON:0000451	48.57	gold quality
fundus of stomach	UBERON:0001160	47.04	gold quality
amygdala	UBERON:0001876	46.57	gold quality
prostate gland	UBERON:0002367	45.95	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.26	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.25	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	43.23	gold quality
body of uterus	UBERON:0009853	43.11	gold quality
hypothalamus	UBERON:0001898	42.48	gold quality
fallopian tube	UBERON:0003889	42.34	silver quality
esophagus	UBERON:0001043	42.00	gold quality
thyroid gland	UBERON:0002046	41.66	silver quality
caudate nucleus	UBERON:0001873	41.28	gold quality
spleen	UBERON:0002106	41.14	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	40.90	silver quality
omental fat pad	UBERON:0010414	40.87	gold quality
corpus callosum	UBERON:0002336	40.72	silver quality
body of stomach	UBERON:0001161	40.36	silver quality
nucleus accumbens	UBERON:0001882	40.28	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.