DTNA-AS1
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Summary
DTNA-AS1 (DTNA antisense RNA 1, HGNC:58208) is a long non-coding RNA gene on chromosome 18q12.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:58208 |
| Approved symbol | DTNA-AS1 |
| Name | DTNA antisense RNA 1 |
| Location | 18q12.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000268873 |
| Ensembl biotype | lncRNA |
| Entrez | 139281650 |
| RNAcentral | URS0002A5670D — lncRNA, 1621 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 3 — 3 lncRNA
ENST00000596954, ENST00000831797, ENST00000831798
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000596954 — 5 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002997723 | 34765934 | 34765994 |
| ENSE00003055710 | 34737795 | 34737880 |
| ENSE00003102725 | 34767543 | 34767663 |
| ENSE00003142488 | 34755458 | 34755635 |
| ENSE00003172241 | 34759933 | 34760063 |
Expression profiles
Bgee: expression breadth broad, 98 present calls, max score 83.37.
Top tissues by expression
98 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 83.37 | gold quality |
| corpus callosum | UBERON:0002336 | 66.98 | gold quality |
| vermiform appendix | UBERON:0001154 | 66.05 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 63.61 | gold quality |
| ganglionic eminence | UBERON:0004023 | 62.12 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 61.69 | gold quality |
| lymph node | UBERON:0000029 | 59.83 | gold quality |
| liver | UBERON:0002107 | 59.55 | gold quality |
| muscle of leg | UBERON:0001383 | 58.70 | gold quality |
| gastrocnemius | UBERON:0001388 | 58.46 | gold quality |
| placenta | UBERON:0001987 | 57.87 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 57.28 | gold quality |
| right lobe of liver | UBERON:0001114 | 57.18 | gold quality |
| stromal cell of endometrium | CL:0002255 | 55.06 | silver quality |
| calcaneal tendon | UBERON:0003701 | 53.98 | gold quality |
| gall bladder | UBERON:0002110 | 53.52 | gold quality |
| sural nerve | UBERON:0015488 | 53.51 | silver quality |
| islet of Langerhans | UBERON:0000006 | 53.22 | gold quality |
| prefrontal cortex | UBERON:0000451 | 52.87 | gold quality |
| endometrium | UBERON:0001295 | 52.50 | silver quality |
| right lobe of thyroid gland | UBERON:0001119 | 52.38 | gold quality |
| monocyte | CL:0000576 | 51.30 | silver quality |
| thyroid gland | UBERON:0002046 | 51.28 | gold quality |
| heart left ventricle | UBERON:0002084 | 50.96 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 50.33 | gold quality |
| heart | UBERON:0000948 | 49.97 | gold quality |
| left coronary artery | UBERON:0001626 | 49.82 | gold quality |
| myometrium | UBERON:0001296 | 49.68 | gold quality |
| blood | UBERON:0000178 | 49.14 | silver quality |
| cortex of kidney | UBERON:0001225 | 49.14 | silver quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.77 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): left ventricular noncompaction 1