DTNB-AS1

Summary

DTNB-AS1 (DTNB antisense RNA 1, HGNC:40198) is a long non-coding RNA gene on chromosome 2p23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40198
Approved symbol	DTNB-AS1
Name	DTNB antisense RNA 1
Location	2p23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224220
Ensembl biotype	lncRNA
Entrez	101929272
RNAcentral	URS00026A221D — lncRNA, 3568 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000352271, ENST00000780548, ENST00000780549, ENST00000780550, ENST00000780551, ENST00000780552

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000352271 — 3 exons

Exon	Start	End
ENSE00001602450	25421117	25421223
ENSE00001694893	25427467	25427643
ENSE00001726035	25426586	25426715

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 85.11.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5039 / max 80.9122, expressed in 45 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19223	0.5039	45

Top tissues by expression

273 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.11	gold quality
epithelium of nasopharynx	UBERON:0001951	80.62	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.97	gold quality
colonic epithelium	UBERON:0000397	78.44	gold quality
vermiform appendix	UBERON:0001154	76.09	gold quality
lymph node	UBERON:0000029	74.34	gold quality
rectum	UBERON:0001052	74.03	gold quality
spleen	UBERON:0002106	73.82	gold quality
bone marrow cell	CL:0002092	73.40	gold quality
caecum	UBERON:0001153	73.37	gold quality
tonsil	UBERON:0002372	71.99	gold quality
sural nerve	UBERON:0015488	71.82	gold quality
duodenum	UBERON:0002114	68.35	gold quality
sperm	CL:0000019	66.50	gold quality
male germ cell	CL:0000015	65.28	gold quality
jejunal mucosa	UBERON:0000399	63.93	silver quality
transverse colon	UBERON:0001157	63.65	gold quality
mucosa of sigmoid colon	UBERON:0004993	63.55	silver quality
mucosa of transverse colon	UBERON:0004991	63.25	gold quality
monocyte	CL:0000576	63.23	gold quality
mononuclear cell	CL:0000842	63.23	gold quality
small intestine	UBERON:0002108	63.15	gold quality
small intestine Peyer’s patch	UBERON:0003454	62.80	gold quality
intestine	UBERON:0000160	62.48	gold quality
pylorus	UBERON:0001166	62.45	gold quality
large intestine	UBERON:0000059	62.29	gold quality
colon	UBERON:0001155	61.42	gold quality
gall bladder	UBERON:0002110	61.33	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	60.97	gold quality
colonic mucosa	UBERON:0000317	60.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.