DUSP5-DT

Summary

DUSP5-DT (DUSP5 divergent transcript, HGNC:55154) is a long non-coding RNA gene on chromosome 10q25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55154
Approved symbol	DUSP5-DT
Name	DUSP5 divergent transcript
Location	10q25.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273143
Ensembl biotype	lncRNA
Entrez	105378481
RNAcentral	URS00026A2553 — lncRNA, 980 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 84 — 84 lncRNA

ENST00000607952, ENST00000609514, ENST00000666621, ENST00000770940, ENST00000770941, ENST00000770942, ENST00000770943, ENST00000770944, ENST00000770945, ENST00000770946, ENST00000770947, ENST00000770948, ENST00000770949, ENST00000770950, ENST00000770951, ENST00000770952, ENST00000770953, ENST00000770954, ENST00000770955, ENST00000770956, ENST00000770957, ENST00000770958, ENST00000770959, ENST00000770960, ENST00000770961, ENST00000770962, ENST00000770963, ENST00000770964, ENST00000770965, ENST00000770966, ENST00000770967, ENST00000770968, ENST00000770969, ENST00000770970, ENST00000770971, ENST00000770972, ENST00000770973, ENST00000770974, ENST00000770975, ENST00000770976, ENST00000770977, ENST00000770978, ENST00000770979, ENST00000770980, ENST00000770981, ENST00000770982, ENST00000770983, ENST00000770984, ENST00000770985, ENST00000770986, ENST00000770987, ENST00000770988, ENST00000770989, ENST00000770990, ENST00000770991, ENST00000770992, ENST00000770993, ENST00000770994, ENST00000770995, ENST00000770996, ENST00000770997, ENST00000770998, ENST00000770999, ENST00000771000, ENST00000771001, ENST00000771002, ENST00000771003, ENST00000771004, ENST00000771005, ENST00000771006, ENST00000771007, ENST00000771008, ENST00000771009, ENST00000771010, ENST00000771011, ENST00000771012, ENST00000771013, ENST00000771014, ENST00000771015, ENST00000771016, ENST00000771017, ENST00000771018, ENST00000771019, ENST00000771020

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607952 — 2 exons

Exon	Start	End
ENSE00003704086	110496119	110496204
ENSE00003706062	110475104	110475226

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 76.97.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2918 / max 66.3031, expressed in 122 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
111392	0.2169	84
111393	0.0560	11
111394	0.0188	2

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	76.97	gold quality
cerebellar cortex	UBERON:0002129	76.91	gold quality
cerebellum	UBERON:0002037	76.88	gold quality
cerebellar hemisphere	UBERON:0002245	76.70	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.05	gold quality
cortical plate	UBERON:0005343	73.04	gold quality
primary visual cortex	UBERON:0002436	70.15	gold quality
sural nerve	UBERON:0015488	69.13	silver quality
islet of Langerhans	UBERON:0000006	67.39	gold quality
muscle tissue	UBERON:0002385	66.69	gold quality
skeletal muscle tissue	UBERON:0001134	66.13	silver quality
liver	UBERON:0002107	66.11	gold quality
right lobe of liver	UBERON:0001114	65.88	gold quality
placenta	UBERON:0001987	65.38	gold quality
monocyte	CL:0000576	65.26	gold quality
bone marrow	UBERON:0002371	63.95	gold quality
calcaneal tendon	UBERON:0003701	63.46	gold quality
smooth muscle tissue	UBERON:0001135	62.31	gold quality
right uterine tube	UBERON:0001302	62.12	gold quality
lower esophagus mucosa	UBERON:0035834	61.07	gold quality
pancreas	UBERON:0001264	60.41	gold quality
myometrium	UBERON:0001296	60.27	gold quality
brain	UBERON:0000955	60.10	gold quality
tonsil	UBERON:0002372	58.81	gold quality
duodenum	UBERON:0002114	58.52	gold quality
blood	UBERON:0000178	58.36	gold quality
stromal cell of endometrium	CL:0002255	58.10	gold quality
Ammon’s horn	UBERON:0001954	57.80	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.95	gold quality
vermiform appendix	UBERON:0001154	56.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.