DYNC1LI2-DT

Summary

DYNC1LI2-DT (DYNC1LI2 divergent transcript, HGNC:52990) is a long non-coding RNA gene on chromosome 16q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52990
Approved symbol	DYNC1LI2-DT
Name	DYNC1LI2 divergent transcript
Location	16q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246777
Ensembl biotype	lncRNA
Entrez	106699570
RNAcentral	URS00008E3A79 — lncRNA, 2920 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000501143

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501143 — 2 exons

Exon	Start	End
ENSE00001980181	66752996	66754740
ENSE00001985625	66751752	66752900

Expression profiles

Bgee: expression breadth broad, 77 present calls, max score 67.83.

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	67.83	silver quality
tongue squamous epithelium	UBERON:0006919	61.81	gold quality
ganglionic eminence	UBERON:0004023	58.97	gold quality
lower lobe of lung	UBERON:0008949	57.99	silver quality
cortical plate	UBERON:0005343	54.47	silver quality
male germ cell	CL:0000015	52.31	gold quality
sperm	CL:0000019	52.18	gold quality
monocyte	CL:0000576	51.28	silver quality
uterine cervix	UBERON:0000002	51.12	gold quality
mononuclear cell	CL:0000842	50.86	silver quality
prefrontal cortex	UBERON:0000451	50.38	silver quality
pancreatic ductal cell	CL:0002079	50.08	silver quality
oviduct epithelium	UBERON:0004804	50.07	gold quality
Brodmann (1909) area 46	UBERON:0006483	49.93	gold quality
bone marrow cell	CL:0002092	49.58	gold quality
islet of Langerhans	UBERON:0000006	49.53	gold quality
epithelial cell of pancreas	CL:0000083	49.48	gold quality
embryo	UBERON:0000922	49.31	silver quality
blood vessel layer	UBERON:0004797	49.29	gold quality
cervix squamous epithelium	UBERON:0006922	49.20	gold quality
hair follicle	UBERON:0002073	49.18	gold quality
pancreas	UBERON:0001264	49.04	silver quality
gall bladder	UBERON:0002110	48.93	gold quality
olfactory bulb	UBERON:0002264	48.92	gold quality
choroid plexus epithelium	UBERON:0003911	48.89	gold quality
myocardium	UBERON:0002349	48.87	gold quality
type B pancreatic cell	CL:0000169	48.83	gold quality
nasal cavity epithelium	UBERON:0005384	48.67	gold quality
cardiac muscle of right atrium	UBERON:0003379	48.55	gold quality
quadriceps femoris	UBERON:0001377	48.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.