DYNLL2-DT

Summary

DYNLL2-DT (DYNLL2 divergent transcript, HGNC:52833) is a long non-coding RNA gene on chromosome 17q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52833
Approved symbol	DYNLL2-DT
Name	DYNLL2 divergent transcript
Location	17q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266290
Ensembl biotype	lncRNA
Entrez	101927666
RNAcentral	URS0000427C40 — lncRNA, 6113 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000584805

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000584805 — 3 exons

Exon	Start	End
ENSE00002720717	58076891	58079259
ENSE00004238613	58082716	58083233
ENSE00004238614	58079362	58082616

Expression profiles

Bgee: expression breadth broad, 19 present calls, max score 98.69.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2501 / max 35.8446, expressed in 65 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
167176	0.2501	65

Top tissues by expression

19 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	98.69	gold quality
pancreas	UBERON:0001264	95.79	gold quality
adrenal gland	UBERON:0002369	85.76	gold quality
small intestine	UBERON:0002108	84.89	gold quality
stomach	UBERON:0000945	82.54	gold quality
skeletal muscle tissue	UBERON:0001134	81.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.04	gold quality
colon	UBERON:0001155	73.63	gold quality
urinary bladder	UBERON:0001255	71.49	silver quality
thyroid gland	UBERON:0002046	69.86	gold quality
thoracic mammary gland	UBERON:0005200	58.22	silver quality
lung	UBERON:0002048	54.40	silver quality
right ovary	UBERON:0002118	51.97	gold quality
testis	UBERON:0000473	51.10	gold quality
blood	UBERON:0000178	49.92	silver quality
left testis	UBERON:0004533	49.59	gold quality
right testis	UBERON:0004534	48.81	gold quality
left ovary	UBERON:0002119	47.26	gold quality
gastrocnemius	UBERON:0001388	36.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.