DYRK3-AS1

Summary

DYRK3-AS1 (DYRK3 antisense RNA 1, HGNC:40199) is a long non-coding RNA gene on chromosome 1q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40199
Approved symbol	DYRK3-AS1
Name	DYRK3 antisense RNA 1
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237605
Ensembl biotype	lncRNA
Entrez	105372876
RNAcentral	URS00026A1E49 — lncRNA, 1077 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000425161, ENST00000654354, ENST00000669393, ENST00000688109, ENST00000790507, ENST00000790508, ENST00000790509, ENST00000790510, ENST00000790511

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425161 — 3 exons

Exon	Start	End
ENSE00004170857	206634191	206634983
ENSE00004170863	206635600	206635696
ENSE00004170870	206636132	206636192

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 88.51.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5577 / max 97.8735, expressed in 199 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
17078	0.5527	196
17079	0.0050	2

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.51	gold quality
left testis	UBERON:0004533	83.40	gold quality
secondary oocyte	CL:0000655	83.36	gold quality
oocyte	CL:0000023	82.97	gold quality
right testis	UBERON:0004534	82.27	gold quality
testis	UBERON:0000473	81.55	gold quality
sperm	CL:0000019	79.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.48	gold quality
pancreatic ductal cell	CL:0002079	75.89	silver quality
bone marrow cell	CL:0002092	70.68	gold quality
adult organism	UBERON:0007023	69.12	gold quality
ventricular zone	UBERON:0003053	66.57	gold quality
cortical plate	UBERON:0005343	66.22	gold quality
colonic epithelium	UBERON:0000397	65.77	silver quality
tibialis anterior	UBERON:0001385	64.87	silver quality
ganglionic eminence	UBERON:0004023	64.58	gold quality
sural nerve	UBERON:0015488	62.79	silver quality
ileal mucosa	UBERON:0000331	62.22	silver quality
stromal cell of endometrium	CL:0002255	60.31	gold quality
granulocyte	CL:0000094	58.50	gold quality
deltoid	UBERON:0001476	58.32	gold quality
monocyte	CL:0000576	58.19	gold quality
islet of Langerhans	UBERON:0000006	58.16	gold quality
epithelial cell of pancreas	CL:0000083	56.58	gold quality
left ventricle myocardium	UBERON:0006566	56.37	gold quality
cardiac muscle of right atrium	UBERON:0003379	55.86	gold quality
gall bladder	UBERON:0002110	55.69	gold quality
smooth muscle tissue	UBERON:0001135	55.10	gold quality
lower esophagus mucosa	UBERON:0035834	54.96	gold quality
tendon of biceps brachii	UBERON:0008188	54.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.