E2F5-DT

Summary

E2F5-DT (E2F5 divergent transcript, HGNC:55393) is a long non-coding RNA gene on chromosome 8q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55393
Approved symbol	E2F5-DT
Name	E2F5 divergent transcript
Location	8q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260493
Ensembl biotype	lncRNA
Entrez	102723322
RNAcentral	URS0000A769AD — lncRNA, 501 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000562577, ENST00000566000, ENST00000812941, ENST00000812942, ENST00000812943, ENST00000812944, ENST00000812945, ENST00000812946, ENST00000812947, ENST00000812948, ENST00000812949, ENST00000812950, ENST00000812951, ENST00000812952, ENST00000812953, ENST00000812954, ENST00000812955, ENST00000812956, ENST00000812957, ENST00000812958

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562577 — 3 exons

Exon	Start	End
ENSE00002578698	85172438	85172472
ENSE00002585640	85172077	85172317
ENSE00004212527	85176831	85177072

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 82.16.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.16	gold quality
sural nerve	UBERON:0015488	72.87	gold quality
right uterine tube	UBERON:0001302	64.87	gold quality
ventricular zone	UBERON:0003053	60.53	gold quality
apex of heart	UBERON:0002098	58.04	gold quality
calcaneal tendon	UBERON:0003701	57.73	gold quality
endometrium	UBERON:0001295	57.48	gold quality
muscle tissue	UBERON:0002385	56.52	gold quality
lymph node	UBERON:0000029	56.32	gold quality
fallopian tube	UBERON:0003889	55.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.18	silver quality
monocyte	CL:0000576	55.00	gold quality
thyroid gland	UBERON:0002046	54.23	gold quality
right lobe of thyroid gland	UBERON:0001119	54.15	gold quality
prefrontal cortex	UBERON:0000451	53.76	gold quality
left lobe of thyroid gland	UBERON:0001120	53.50	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.25	gold quality
rectum	UBERON:0001052	52.82	gold quality
tibial nerve	UBERON:0001323	52.72	gold quality
superior frontal gyrus	UBERON:0002661	52.71	gold quality
blood	UBERON:0000178	52.67	gold quality
liver	UBERON:0002107	52.48	gold quality
left testis	UBERON:0004533	52.44	gold quality
tonsil	UBERON:0002372	52.09	gold quality
testis	UBERON:0000473	52.07	gold quality
nucleus accumbens	UBERON:0001882	52.00	gold quality
hypothalamus	UBERON:0001898	51.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	51.90	gold quality
caudate nucleus	UBERON:0001873	51.63	gold quality
amygdala	UBERON:0001876	51.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.