EAF1-AS1

Summary

EAF1-AS1 (EAF1 antisense RNA 1, HGNC:42328) is a long non-coding RNA gene on chromosome 3p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42328
Approved symbol	EAF1-AS1
Name	EAF1 antisense RNA 1
Location	3p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249786
Ensembl biotype	lncRNA
Entrez	100873956
RNAcentral	URS00004CF72D — lncRNA, 1207 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000494875, ENST00000593876, ENST00000594820, ENST00000595627, ENST00000595975, ENST00000597949, ENST00000599742, ENST00000608780, ENST00000609310, ENST00000610011

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000494875 — 2 exons

Exon	Start	End
ENSE00001863029	15439064	15439388
ENSE00003153445	15440261	15440566

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 89.57.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0086 / max 5.4135, expressed in 4 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41278	0.0086	4

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	89.57	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.76	gold quality
corpus callosum	UBERON:0002336	79.82	gold quality
colonic epithelium	UBERON:0000397	76.92	gold quality
testis	UBERON:0000473	75.25	gold quality
right testis	UBERON:0004534	75.13	gold quality
left testis	UBERON:0004533	74.94	gold quality
sural nerve	UBERON:0015488	74.04	gold quality
skeletal muscle tissue	UBERON:0001134	71.51	gold quality
leukocyte	CL:0000738	71.19	gold quality
monocyte	CL:0000576	71.14	gold quality
calcaneal tendon	UBERON:0003701	70.82	gold quality
bone marrow cell	CL:0002092	70.70	silver quality
blood	UBERON:0000178	70.67	gold quality
ganglionic eminence	UBERON:0004023	70.27	gold quality
fallopian tube	UBERON:0003889	69.76	gold quality
muscle tissue	UBERON:0002385	69.73	gold quality
endometrium	UBERON:0001295	69.54	gold quality
cerebellum	UBERON:0002037	68.73	gold quality
cerebellar hemisphere	UBERON:0002245	68.72	gold quality
ventricular zone	UBERON:0003053	68.71	gold quality
cerebellar cortex	UBERON:0002129	68.68	gold quality
bone marrow	UBERON:0002371	68.28	gold quality
granulocyte	CL:0000094	67.92	gold quality
cortical plate	UBERON:0005343	67.79	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.77	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.68	gold quality
liver	UBERON:0002107	67.35	gold quality
left uterine tube	UBERON:0001303	67.07	gold quality
right lobe of liver	UBERON:0001114	65.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.