ECE1-AS1

Summary

ECE1-AS1 (ECE1 antisense RNA 1, HGNC:40203) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40203
Approved symbol	ECE1-AS1
Name	ECE1 antisense RNA 1
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231105
Ensembl biotype	lncRNA
Entrez	100506801
RNAcentral	URS000075BCD7 — lncRNA, 2574 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000449034, ENST00000655030

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449034 — 3 exons

Exon	Start	End
ENSE00001619513	21293290	21293743
ENSE00001736244	21298027	21299774
ENSE00001747894	21293934	21294210

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 77.18.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3372 / max 118.8189, expressed in 84 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1145	0.2222	56
201393	0.1151	46

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.18	gold quality
bone marrow cell	CL:0002092	75.45	gold quality
sural nerve	UBERON:0015488	68.96	gold quality
colonic epithelium	UBERON:0000397	68.40	silver quality
lymph node	UBERON:0000029	68.06	gold quality
bone marrow	UBERON:0002371	67.86	gold quality
blood	UBERON:0000178	67.06	gold quality
tonsil	UBERON:0002372	65.92	gold quality
vermiform appendix	UBERON:0001154	63.64	gold quality
granulocyte	CL:0000094	63.06	gold quality
skeletal muscle tissue	UBERON:0001134	61.72	silver quality
stromal cell of endometrium	CL:0002255	61.41	gold quality
spleen	UBERON:0002106	60.97	gold quality
adrenal tissue	UBERON:0018303	60.37	gold quality
duodenum	UBERON:0002114	58.97	gold quality
ventricular zone	UBERON:0003053	58.66	silver quality
ganglionic eminence	UBERON:0004023	56.49	silver quality
leukocyte	CL:0000738	55.40	gold quality
urinary bladder	UBERON:0001255	54.57	gold quality
right testis	UBERON:0004534	54.19	gold quality
small intestine	UBERON:0002108	53.33	gold quality
liver	UBERON:0002107	53.00	silver quality
small intestine Peyer’s patch	UBERON:0003454	52.64	gold quality
apex of heart	UBERON:0002098	52.26	gold quality
gall bladder	UBERON:0002110	52.26	gold quality
monocyte	CL:0000576	51.73	silver quality
thoracic mammary gland	UBERON:0005200	51.71	gold quality
subcutaneous adipose tissue	UBERON:0002190	51.48	gold quality
left testis	UBERON:0004533	51.40	gold quality
testis	UBERON:0000473	51.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.