EDNRB-AS1

Summary

EDNRB-AS1 (EDNRB antisense RNA 1, HGNC:49045) is a long non-coding RNA gene on chromosome 13q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49045
Approved symbol	EDNRB-AS1
Name	EDNRB antisense RNA 1
Location	13q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225579
Ensembl biotype	lncRNA
Entrez	100505518
RNAcentral	URS000075A847 — lncRNA, 2445 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000422405, ENST00000664378, ENST00000667150, ENST00000724134, ENST00000724135, ENST00000724136, ENST00000724137, ENST00000724138, ENST00000724139, ENST00000724140

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422405 — 5 exons

Exon	Start	End
ENSE00001618666	77830553	77830603
ENSE00001649196	77833733	77833950
ENSE00001664258	77829028	77829102
ENSE00001746488	77828222	77828415
ENSE00001763422	77833365	77833427

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 72.06.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.06	silver quality
ventricular zone	UBERON:0003053	60.06	silver quality
ganglionic eminence	UBERON:0004023	59.16	gold quality
monocyte	CL:0000576	56.30	gold quality
granulocyte	CL:0000094	53.29	gold quality
endometrium	UBERON:0001295	53.13	gold quality
right testis	UBERON:0004534	53.04	gold quality
placenta	UBERON:0001987	52.49	gold quality
lymph node	UBERON:0000029	52.43	gold quality
skeletal muscle tissue	UBERON:0001134	52.07	silver quality
bone marrow	UBERON:0002371	51.44	silver quality
prostate gland	UBERON:0002367	51.29	gold quality
left testis	UBERON:0004533	51.28	gold quality
testis	UBERON:0000473	51.26	gold quality
prefrontal cortex	UBERON:0000451	51.21	gold quality
blood	UBERON:0000178	50.47	silver quality
superior frontal gyrus	UBERON:0002661	49.74	gold quality
vermiform appendix	UBERON:0001154	49.18	gold quality
muscle of leg	UBERON:0001383	48.81	silver quality
islet of Langerhans	UBERON:0000006	48.07	gold quality
gastrocnemius	UBERON:0001388	47.62	gold quality
liver	UBERON:0002107	46.56	silver quality
heart left ventricle	UBERON:0002084	46.41	silver quality
tonsil	UBERON:0002372	46.16	gold quality
frontal cortex	UBERON:0001870	45.91	gold quality
right lobe of liver	UBERON:0001114	45.84	silver quality
right coronary artery	UBERON:0001625	45.84	gold quality
gall bladder	UBERON:0002110	45.19	gold quality
pituitary gland	UBERON:0000007	45.16	gold quality
urinary bladder	UBERON:0001255	44.86	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.