EFCAB13-DT
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Also known as THCAT158
Summary
EFCAB13-DT (EFCAB13 divergent transcript, HGNC:55338) is a long non-coding RNA gene on chromosome 17q21.32.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:55338 |
| Approved symbol | EFCAB13-DT |
| Name | EFCAB13 divergent transcript |
| Location | 17q21.32 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | THCAT158 |
| Ensembl gene | ENSG00000263293 |
| Ensembl biotype | lncRNA |
| Entrez | 102724508 |
| RNAcentral | URS000075A626 — lncRNA, 702 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 33 — 33 lncRNA
ENST00000425159, ENST00000572695, ENST00000575039, ENST00000575291, ENST00000576345, ENST00000619646, ENST00000688561, ENST00000691039, ENST00000701693, ENST00000702305, ENST00000702530, ENST00000783715, ENST00000783716, ENST00000783717, ENST00000783718, ENST00000783719, ENST00000783720, ENST00000783721, ENST00000783722, ENST00000783723, ENST00000783724, ENST00000783725, ENST00000783726, ENST00000783727, ENST00000783728, ENST00000783729, ENST00000783730, ENST00000783731, ENST00000783732, ENST00000783733, ENST00000783734, ENST00000783735, ENST00000783736
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000425159 — 6 exons
| Exon | Start | End |
|---|---|---|
| ENSE00004028126 | 47490166 | 47490295 |
| ENSE00004028127 | 47456684 | 47456793 |
| ENSE00004028130 | 47482992 | 47483090 |
| ENSE00004028131 | 47491015 | 47491192 |
| ENSE00004158031 | 47450138 | 47450878 |
| ENSE00004158034 | 47492394 | 47492498 |
Expression profiles
Bgee: expression breadth ubiquitous, 155 present calls, max score 94.15.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2889 / max 11.4203, expressed in 112 samples.
FANTOM5 promoters (1 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 166601 | 0.2889 | 112 |
Top tissues by expression
253 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 94.15 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 91.14 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 81.72 | gold quality |
| ascending aorta | UBERON:0001496 | 80.95 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 80.84 | gold quality |
| thoracic aorta | UBERON:0001515 | 80.69 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 79.43 | gold quality |
| right coronary artery | UBERON:0001625 | 79.39 | gold quality |
| aorta | UBERON:0000947 | 79.37 | gold quality |
| thyroid gland | UBERON:0002046 | 79.09 | gold quality |
| right testis | UBERON:0004534 | 79.04 | gold quality |
| popliteal artery | UBERON:0002250 | 78.78 | gold quality |
| tibial artery | UBERON:0007610 | 78.78 | gold quality |
| left testis | UBERON:0004533 | 78.40 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 76.36 | gold quality |
| left coronary artery | UBERON:0001626 | 76.24 | gold quality |
| testis | UBERON:0000473 | 75.66 | gold quality |
| coronary artery | UBERON:0001621 | 74.76 | gold quality |
| monocyte | CL:0000576 | 74.73 | gold quality |
| sperm | CL:0000019 | 74.36 | silver quality |
| leukocyte | CL:0000738 | 74.02 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 72.62 | gold quality |
| islet of Langerhans | UBERON:0000006 | 72.61 | gold quality |
| lower esophagus | UBERON:0013473 | 72.55 | gold quality |
| metanephros cortex | UBERON:0010533 | 72.38 | gold quality |
| left uterine tube | UBERON:0001303 | 72.29 | gold quality |
| colonic epithelium | UBERON:0000397 | 71.43 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 70.61 | gold quality |
| smooth muscle tissue | UBERON:0001135 | 70.20 | gold quality |
| tibial nerve | UBERON:0001323 | 68.37 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.94 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): bleeding disorder, platelet-type, 24, Glanzmann thrombasthenia, Glanzmann thrombasthenia 1, Glanzmann thrombasthenia 2, hyper-IgE recurrent infection syndrome 1, autosomal dominant, myocardial infarction, susceptibility to, platelet-type bleeding disorder 16, thrombocytopenia