EFCAB6-AS1

Summary

EFCAB6-AS1 (EFCAB6 antisense RNA 1, HGNC:39999) is a long non-coding RNA gene on chromosome 22q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39999
Approved symbol	EFCAB6-AS1
Name	EFCAB6 antisense RNA 1
Location	22q13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	CITF22-123F2.1
Ensembl gene	ENSG00000223843
Ensembl biotype	lncRNA
Entrez	100874197
RNAcentral	URS000075A3A2 — lncRNA, 1997 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000431327, ENST00000656483, ENST00000836181

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431327 — 3 exons

Exon	Start	End
ENSE00001640191	43534853	43537117
ENSE00001659546	43518477	43518597
ENSE00001729318	43516107	43516376

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 82.85.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.85	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.23	gold quality
cortical plate	UBERON:0005343	65.49	gold quality
bone marrow cell	CL:0002092	64.97	silver quality
tonsil	UBERON:0002372	59.25	silver quality
ventricular zone	UBERON:0003053	58.42	silver quality
bone marrow	UBERON:0002371	58.39	silver quality
skeletal muscle tissue	UBERON:0001134	56.50	silver quality
ganglionic eminence	UBERON:0004023	56.47	silver quality
muscle tissue	UBERON:0002385	55.86	silver quality
right uterine tube	UBERON:0001302	55.30	gold quality
leukocyte	CL:0000738	54.10	silver quality
monocyte	CL:0000576	53.06	gold quality
primary visual cortex	UBERON:0002436	52.81	gold quality
blood	UBERON:0000178	52.62	silver quality
stromal cell of endometrium	CL:0002255	52.37	silver quality
superior frontal gyrus	UBERON:0002661	51.82	gold quality
urinary bladder	UBERON:0001255	51.77	silver quality
calcaneal tendon	UBERON:0003701	51.14	silver quality
prefrontal cortex	UBERON:0000451	50.76	silver quality
anterior cingulate cortex	UBERON:0009835	50.72	gold quality
lymph node	UBERON:0000029	50.39	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	49.89	gold quality
cerebral cortex	UBERON:0000956	49.82	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	49.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.69	gold quality
frontal cortex	UBERON:0001870	49.48	gold quality
Ammon’s horn	UBERON:0001954	49.24	gold quality
vermiform appendix	UBERON:0001154	48.88	gold quality
liver	UBERON:0002107	48.31	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.