EGLN3-AS1

Summary

EGLN3-AS1 (EGLN3 antisense RNA 1, HGNC:49077) is a long non-coding RNA gene on chromosome 14q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49077
Approved symbol	EGLN3-AS1
Name	EGLN3 antisense RNA 1
Location	14q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258897
Ensembl biotype	lncRNA
Entrez	105370445
RNAcentral	URS00026A27F6 — lncRNA, 3486 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000555922

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000555922 — 3 exons

Exon	Start	End
ENSE00002452073	34040097	34040170
ENSE00002460557	34041205	34041269
ENSE00002467005	34059132	34059300

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 73.83.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1408 / max 153.3061, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
139180	0.1268	5
139181	0.0139	3

Top tissues by expression

73 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
placenta	UBERON:0001987	73.83	gold quality
myometrium	UBERON:0001296	71.07	gold quality
islet of Langerhans	UBERON:0000006	69.77	gold quality
sural nerve	UBERON:0015488	67.09	silver quality
duodenum	UBERON:0002114	65.53	gold quality
monocyte	CL:0000576	65.46	gold quality
blood	UBERON:0000178	60.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.78	gold quality
gall bladder	UBERON:0002110	60.48	gold quality
bone marrow	UBERON:0002371	60.14	gold quality
vermiform appendix	UBERON:0001154	57.85	gold quality
corpus callosum	UBERON:0002336	57.16	gold quality
right lobe of liver	UBERON:0001114	55.66	gold quality
gastrocnemius	UBERON:0001388	54.98	gold quality
liver	UBERON:0002107	54.59	gold quality
heart left ventricle	UBERON:0002084	52.66	gold quality
body of pancreas	UBERON:0001150	52.54	gold quality
heart	UBERON:0000948	52.52	gold quality
tibial artery	UBERON:0007610	52.36	gold quality
popliteal artery	UBERON:0002250	52.29	gold quality
right ovary	UBERON:0002118	52.08	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	52.03	gold quality
Ammon’s horn	UBERON:0001954	51.52	gold quality
tibial nerve	UBERON:0001323	51.06	gold quality
small intestine	UBERON:0002108	50.90	gold quality
ascending aorta	UBERON:0001496	50.84	gold quality
intestine	UBERON:0000160	50.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	49.93	gold quality
colon	UBERON:0001155	49.81	gold quality
right atrium auricular region	UBERON:0006631	49.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.