EIF1AX-AS1

Summary

EIF1AX-AS1 (EIF1AX antisense RNA 1, HGNC:40208) is a long non-coding RNA gene on chromosome Xp22.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40208
Approved symbol	EIF1AX-AS1
Name	EIF1AX antisense RNA 1
Location	Xp22.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225037
Ensembl biotype	lncRNA
Entrez	100874078
RNAcentral	URS00003C9FE4 — lncRNA, 378 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424026

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424026 — 2 exons

Exon	Start	End
ENSE00001737050	20139968	20140235
ENSE00001744351	20140335	20140444

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 77.19.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	77.19	gold quality
colonic epithelium	UBERON:0000397	75.45	gold quality
bone marrow	UBERON:0002371	71.61	gold quality
calcaneal tendon	UBERON:0003701	71.18	gold quality
bone marrow cell	CL:0002092	70.62	silver quality
adrenal tissue	UBERON:0018303	69.11	gold quality
gall bladder	UBERON:0002110	67.85	gold quality
monocyte	CL:0000576	66.29	gold quality
leukocyte	CL:0000738	66.03	gold quality
endometrium	UBERON:0001295	63.91	gold quality
lymph node	UBERON:0000029	63.07	gold quality
vermiform appendix	UBERON:0001154	60.56	gold quality
islet of Langerhans	UBERON:0000006	60.28	gold quality
blood	UBERON:0000178	59.92	gold quality
smooth muscle tissue	UBERON:0001135	59.73	gold quality
muscle of leg	UBERON:0001383	58.93	gold quality
liver	UBERON:0002107	58.56	gold quality
tonsil	UBERON:0002372	58.06	silver quality
prefrontal cortex	UBERON:0000451	57.47	gold quality
superior frontal gyrus	UBERON:0002661	57.44	gold quality
corpus callosum	UBERON:0002336	57.18	gold quality
urinary bladder	UBERON:0001255	56.97	gold quality
ectocervix	UBERON:0012249	56.73	gold quality
right lobe of liver	UBERON:0001114	56.47	gold quality
uterine cervix	UBERON:0000002	55.67	gold quality
pancreas	UBERON:0001264	55.48	gold quality
kidney	UBERON:0002113	55.18	gold quality
gastrocnemius	UBERON:0001388	54.84	gold quality
granulocyte	CL:0000094	54.83	gold quality
body of pancreas	UBERON:0001150	54.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.21

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA EIF1AX-AS1 promotes endometrial cancer cell apoptosis by affecting EIF1AX mRNA stabilization. (PMID:35080085)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.