EIF2AK3-AS1

Summary

EIF2AK3-AS1 (EIF2AK3 antisense RNA 1, HGNC:58177) is a long non-coding RNA gene on chromosome 2p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58177
Approved symbol	EIF2AK3-AS1
Name	EIF2AK3 antisense RNA 1
Location	2p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225420
Ensembl biotype	lncRNA
Entrez	101928371
RNAcentral	URS000075EFC4 — lncRNA, 1770 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000413234, ENST00000739662, ENST00000739663, ENST00000739664

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413234 — 3 exons

Exon	Start	End
ENSE00001606068	88538720	88539254
ENSE00001607023	88574514	88575610
ENSE00001765133	88540065	88540179

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 79.32.

Top tissues by expression

211 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.32	gold quality
bone marrow cell	CL:0002092	75.15	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.82	gold quality
colonic epithelium	UBERON:0000397	64.59	silver quality
tendon of biceps brachii	UBERON:0008188	62.13	silver quality
sural nerve	UBERON:0015488	61.51	silver quality
ventricular zone	UBERON:0003053	59.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.71	gold quality
epithelium of nasopharynx	UBERON:0001951	59.65	gold quality
tendon	UBERON:0000043	59.36	silver quality
esophagus squamous epithelium	UBERON:0006920	54.55	gold quality
calcaneal tendon	UBERON:0003701	54.15	silver quality
cartilage tissue	UBERON:0002418	53.75	gold quality
monocyte	CL:0000576	53.67	silver quality
bone marrow	UBERON:0002371	53.46	gold quality
sperm	CL:0000019	52.48	gold quality
blood	UBERON:0000178	52.34	gold quality
tonsil	UBERON:0002372	51.42	silver quality
decidua	UBERON:0002450	51.06	gold quality
muscle of leg	UBERON:0001383	50.72	gold quality
medial globus pallidus	UBERON:0002477	50.49	gold quality
gastrocnemius	UBERON:0001388	50.42	gold quality
right atrium auricular region	UBERON:0006631	49.99	gold quality
ectocervix	UBERON:0012249	49.59	gold quality
cardiac atrium	UBERON:0002081	49.53	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.46	gold quality
lower esophagus mucosa	UBERON:0035834	49.39	gold quality
adrenal gland	UBERON:0002369	49.06	gold quality
islet of Langerhans	UBERON:0000006	49.02	gold quality
adrenal tissue	UBERON:0018303	49.00	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.