EIF2AK3-DT

Summary

EIF2AK3-DT (EIF2AK3 divergent transcript, HGNC:54066) is a long non-coding RNA gene on chromosome 2p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54066
Approved symbol	EIF2AK3-DT
Name	EIF2AK3 divergent transcript
Location	2p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234028
Ensembl biotype	lncRNA
Entrez	101928403
RNAcentral	URS0000A769B7 — lncRNA, 1347 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000453008, ENST00000606164, ENST00000688818, ENST00000790078, ENST00000790079, ENST00000790080

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453008 — 2 exons

Exon	Start	End
ENSE00004169962	88627539	88628732
ENSE00004169968	88631400	88631825

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 77.32.

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	77.32	gold quality
oviduct epithelium	UBERON:0004804	76.40	gold quality
islet of Langerhans	UBERON:0000006	72.63	gold quality
pancreatic ductal cell	CL:0002079	70.12	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	69.99	gold quality
tibialis anterior	UBERON:0001385	69.92	silver quality
right uterine tube	UBERON:0001302	69.40	gold quality
sural nerve	UBERON:0015488	69.11	silver quality
germinal epithelium of ovary	UBERON:0001304	68.02	silver quality
ileal mucosa	UBERON:0000331	67.67	gold quality
granulocyte	CL:0000094	66.95	gold quality
calcaneal tendon	UBERON:0003701	66.29	gold quality
ventricular zone	UBERON:0003053	66.07	gold quality
fallopian tube	UBERON:0003889	65.78	gold quality
pituitary gland	UBERON:0000007	65.43	gold quality
pancreas	UBERON:0001264	65.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.31	gold quality
bronchial epithelial cell	CL:0002328	65.13	silver quality
adenohypophysis	UBERON:0002196	64.36	gold quality
vermiform appendix	UBERON:0001154	64.34	gold quality
lymph node	UBERON:0000029	64.16	gold quality
bronchus	UBERON:0002185	64.01	silver quality
palpebral conjunctiva	UBERON:0001812	63.74	gold quality
buccal mucosa cell	CL:0002336	63.62	silver quality
stromal cell of endometrium	CL:0002255	63.48	gold quality
tibia	UBERON:0000979	63.38	silver quality
rectum	UBERON:0001052	63.38	gold quality
ovary	UBERON:0000992	63.22	gold quality
colonic epithelium	UBERON:0000397	62.84	silver quality
left ovary	UBERON:0002119	62.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.