ELDR

Summary

ELDR (EGFR long non-coding downstream RNA, HGNC:49511) is a long non-coding RNA gene on chromosome 7p11.2.

Predicted to act upstream of or within regulation of gene expression and response to wounding.

Source: NCBI Gene 102725541 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49511
Approved symbol	ELDR
Name	EGFR long non-coding downstream RNA
Location	7p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	Fabl
Ensembl gene	ENSG00000280890
Ensembl biotype	lncRNA
OMIM	618217
Entrez	102725541
RNAcentral	URS000075CBD6 — lncRNA, 470 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000626532, ENST00000782315, ENST00000782316, ENST00000782317, ENST00000782318, ENST00000782319, ENST00000782320, ENST00000782321, ENST00000782322, ENST00000782323, ENST00000782324, ENST00000782325, ENST00000782326, ENST00000782327, ENST00000782328, ENST00000782329

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000626532 — 4 exons

Exon	Start	End
ENSE00003763629	55255531	55255635
ENSE00003769738	55238562	55238666
ENSE00003771635	55255187	55255418
ENSE00003771982	55235965	55238463

Expression profiles

Bgee: expression breadth broad, 15 present calls, max score 79.60.

Top tissues by expression

15 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.60	silver quality
liver	UBERON:0002107	56.09	gold quality
endometrium	UBERON:0001295	54.18	gold quality
thyroid gland	UBERON:0002046	50.93	gold quality
blood	UBERON:0000178	47.98	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.23	gold quality
adenohypophysis	UBERON:0002196	45.96	gold quality
placenta	UBERON:0001987	45.69	silver quality
small intestine	UBERON:0002108	45.27	silver quality
right lobe of liver	UBERON:0001114	43.18	silver quality
pituitary gland	UBERON:0000007	42.06	gold quality
left testis	UBERON:0004533	36.89	silver quality
gastrocnemius	UBERON:0001388	36.88	silver quality
testis	UBERON:0000473	36.55	silver quality
right testis	UBERON:0004534	36.49	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Emerging role of lncRNA ELDR in development and cancer. (PMID:33860640)
• Long noncoding RNA ELDR promotes cell cycle progression in normal oral keratinocytes through induction of a CTCF-FOXM1-AURKA signaling axis. (PMID:35378133)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.