ELMOD1

gene
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Also known as DKFZp547C176

Summary

ELMOD1 (ELMO domain containing 1, HGNC:25334) is a protein-coding gene on chromosome 11q22.3, encoding ELMO domain-containing protein 1 (Q8N336). Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.

Enables GTPase activator activity. Predicted to act upstream of or within cilium assembly and protein transport. Predicted to be active in Golgi apparatus; cilium; and glutamatergic synapse.

Source: NCBI Gene 55531 — RefSeq curated summary.

At a glance

  • Gene–disease (curated): neurodevelopmental disorder (Limited, GenCC)
  • GWAS associations: 3
  • Clinical variants (ClinVar): 56 total
  • MANE Select transcript: NM_018712

Identifiers

Gene identifiers

FieldValue
HGNC IDHGNC:25334
Approved symbolELMOD1
NameELMO domain containing 1
Location11q22.3
Locus typegene with protein product
StatusApproved
AliasesDKFZp547C176
Ensembl geneENSG00000110675
Ensembl biotypeprotein_coding
OMIM615456
Entrez55531

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 5 protein_coding, 3 protein_coding_CDS_not_defined, 1 retained_intron

ENST00000265840, ENST00000443271, ENST00000524378, ENST00000527036, ENST00000529675, ENST00000531234, ENST00000534236, ENST00000959906, ENST00000959907

RefSeq mRNA: 3 — MANE Select: NM_018712 NM_001130037, NM_001308018, NM_018712

CCDS: CCDS44723, CCDS44724, CCDS76472

Canonical transcript exons

ENST00000265840 — 12 exons

ExonStartEnd
ENSE00000746412107650335107650403
ENSE00000795444107654172107654222
ENSE00001005031107650885107650908
ENSE00001101496107655933107656066
ENSE00001132697107647468107647601
ENSE00001185310107635636107635765
ENSE00001185313107631580107631677
ENSE00001185317107630700107630728
ENSE00001630985107665025107666779
ENSE00002181706107591147107591409
ENSE00003523396107630417107630562
ENSE00003530847107618105107618206

Expression profiles

Bgee: expression breadth ubiquitous, 192 present calls, max score 98.79.

FANTOM5 (CAGE): breadth broad, TPM avg 7.1725 / max 309.4794, expressed in 458 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter IDTPM avgSamples expressed
1165042.7963306
1165002.6177230
1165060.9254123
1165070.384692
1165050.132373
1165020.108460
1165010.106662
1165030.101260

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

TissueAnatomy IDExpression scoreQuality
lateral nuclear group of thalamusUBERON:000273698.79gold quality
upper arm skinUBERON:000426398.19gold quality
cortical plateUBERON:000534397.84gold quality
Brodmann (1909) area 46UBERON:000648397.54gold quality
cerebellar vermisUBERON:000472097.49gold quality
endothelial cellCL:000011596.91gold quality
Brodmann (1909) area 23UBERON:001355496.69gold quality
lateral globus pallidusUBERON:000247696.61gold quality
ponsUBERON:000098896.22gold quality
middle temporal gyrusUBERON:000277196.18gold quality
superior vestibular nucleusUBERON:000722795.89gold quality
substantia nigra pars compactaUBERON:000196595.79gold quality
superior frontal gyrusUBERON:000266195.38gold quality
parietal lobeUBERON:000187295.15gold quality
postcentral gyrusUBERON:000258194.89gold quality
occipital lobeUBERON:000202194.78gold quality
primary visual cortexUBERON:000243694.57gold quality
substantia nigra pars reticulataUBERON:000196694.23gold quality
prefrontal cortexUBERON:000045193.97gold quality
nucleus accumbensUBERON:000188293.80gold quality
medulla oblongataUBERON:000189693.43gold quality
frontal cortexUBERON:000187093.15gold quality
dorsolateral prefrontal cortexUBERON:000983493.15gold quality
frontal lobeUBERON:001652593.15gold quality
upper leg skinUBERON:000426292.84gold quality
Brodmann (1909) area 9UBERON:001354092.68gold quality
entorhinal cortexUBERON:000272892.52gold quality
neocortexUBERON:000195092.30gold quality
cerebral cortexUBERON:000095692.23gold quality
ventral tegmental areaUBERON:000269191.64gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

ExperimentMarker?Max mean expression
E-GEOD-75367yes40.32
E-ANND-3yes5.01

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

136 targeting ELMOD1, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNAMax scoreAvg scoremiRNA target_count
HSA-MIR-3163100.0077.238605
HSA-MIR-3064-3P100.0070.091254
HSA-MIR-4510100.0066.602050
HSA-MIR-6127100.0066.762188
HSA-MIR-6129100.0066.462080
HSA-MIR-6130100.0066.692012
HSA-MIR-6133100.0066.482064
HSA-MIR-200B-3P100.0073.312693
HSA-MIR-200C-3P100.0073.352685
HSA-MIR-429100.0073.442698
HSA-MIR-5692A100.0074.406850
HSA-MIR-513A-5P100.0069.772465
HSA-MIR-3120-5P100.0065.56965
HSA-MIR-34A-5P99.9971.211784
HSA-MIR-449A99.9971.051776
HSA-MIR-366299.9973.825684
HSA-MIR-428299.9975.366408
HSA-MIR-569699.9872.364487
HSA-MIR-27A-3P99.9872.132955
HSA-MIR-27B-3P99.9872.132955
HSA-MIR-998599.9872.112939
HSA-MIR-34C-5P99.9770.451577
HSA-MIR-449B-5P99.9770.261580
HSA-MIR-548AN99.9770.912817
HSA-MIR-570-3P99.9672.414910
HSA-MIR-495-3P99.9672.814197
HSA-MIR-568899.9673.234504
HSA-MIR-391099.9571.132227
HSA-MIR-141-3P99.9472.792421
HSA-MIR-200A-3P99.9472.682420

Literature-anchored findings (GeneRIF, showing 3)

  • The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity. (PMID:24616099)
  • Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1-Dock180 and intersectin 1/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 = ELMO domain-containing protein 1; Dock180 = dedicator of cytokinesis protein 1 180 kDa) (PMID:28600358)
  • ELMOD1 mutation segregates with intellectual disability and autism spectrum disorder in Iranian family. (PMID:31327155)

Cross-species orthologs

3 orthologs

OrganismSymbolGene ID
danio_rerioelmod1ENSDARG00000062056
mus_musculusElmod1ENSMUSG00000041986
rattus_norvegicusElmod1ENSRNOG00000009054

Paralogs (5): ELMO2 (ENSG00000062598), ELMO3 (ENSG00000102890), ELMOD3 (ENSG00000115459), ELMO1 (ENSG00000155849), ELMOD2 (ENSG00000179387)

Protein

Protein identifiers

ELMO domain-containing protein 1Q8N336 (reviewed: Q8N336)

All UniProt accessions (2): Q8N336, E9PLM8

UniProt curated annotations — full annotation on UniProt →

Function. Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.

Isoforms (3)

UniProt IDNamesCanonical?
Q8N336-11yes
Q8N336-22
Q8N336-33

RefSeq proteins (3): NP_001123509, NP_001294947, NP_061182* (*=MANE)

Domains & families (InterPro)

IDNameType
IPR006816ELMO_domDomain
IPR050868ELMO_domain-containingFamily

Pfam: PF04727

UniProt features (4 total): splice variant 2, chain 1, domain 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

ModelpLDDTFraction very-high
AF-Q8N336-F190.800.72

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 122 (showing top): GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8_TCELL_IFNAR_KO_UP, BENPORATH_ES_WITH_H3K27ME3, PEREZ_TP63_TARGETS, chr11q22, IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR, ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP, EFC_Q6, GOBP_CILIUM_ORGANIZATION, E4F1_Q6, GOBP_ORGANELLE_ASSEMBLY, PEREZ_TP53_AND_TP63_TARGETS, GOBP_CELL_PROJECTION_ORGANIZATION, YNGTTNNNATT_UNKNOWN, LEE_TARGETS_OF_PTCH1_AND_SUFU_DN, TGGAAA_NFAT_Q4_01

GO Biological Process (3): protein transport (GO:0015031), cilium assembly (GO:0060271), intracellular protein localization (GO:0008104)

GO Molecular Function (1): GTPase activator activity (GO:0005096)

GO Cellular Component (4): Golgi apparatus (GO:0005794), cilium (GO:0005929), glutamatergic synapse (GO:0098978), synapse (GO:0045202)

GO top-level categories

Rollup of top GO terms by namespace:

CategoryTerms
transport1
intracellular protein localization1
establishment of protein localization1
axoneme assembly1
intraciliary transport involved in cilium assembly1
cilium organization1
protein localization to cilium1
organelle assembly1
trans-Golgi to periciliary membrane compartment transport1
plasma membrane bounded cell projection assembly1
ciliary transition zone assembly1
macromolecule localization1
GTPase activity1
enzyme activator activity1
GTPase regulator activity1
cytoplasm1
endomembrane system1
intracellular membrane-bounded organelle1
intraciliary transport particle1
membrane-bounded organelle1
plasma membrane bounded cell projection1
synapse1
cell junction1

Protein interactions and networks

STRING

1042 interactions, top by confidence (×1000):

Protein AProtein BPartner UniProtScore
ELMOD1ELMOD3Q96FG2791
ELMOD1ARL2P36404569
ELMOD1POGLUT3Q7Z4H8554
ELMOD1SLC35F2Q8IXU6540
ELMOD1RASA1P20936516
ELMOD1DOCK1Q14185513
ELMOD1ARL3P36405501
ELMOD1ELMO2Q96JJ3490
ELMOD1ELMO3Q96BJ8486
ELMOD1ELMO1Q92556433
ELMOD1ARF6P26438400
ELMOD1TBC1D24Q9ULP9364
ELMOD1PIP5K1BP78518362
ELMOD1CYTH2Q99418359
ELMOD1MYSM1Q5VVJ2351

IntAct

8 interactions, top by confidence:

ABTypeScore
ELMOD1LDHCpsi-mi:“MI:0914”(association)0.530
ELMOD1S100A10psi-mi:“MI:0915”(physical association)0.400
ELMOD1RHOApsi-mi:“MI:0915”(physical association)0.400
ELMOD1THG1Lpsi-mi:“MI:0915”(physical association)0.370
ITM2BILVBLpsi-mi:“MI:0914”(association)0.350
TMED7ATP9Apsi-mi:“MI:0914”(association)0.350

BioGRID (18): SELENBP1 (Affinity Capture-MS), LRRC15 (Affinity Capture-MS), PKP3 (Affinity Capture-MS), LGALS3 (Affinity Capture-MS), DSG4 (Affinity Capture-MS), ELMOD1 (Two-hybrid), LRRC15 (Affinity Capture-MS), LDHC (Affinity Capture-MS), PKP3 (Affinity Capture-MS), ELMOD1 (Affinity Capture-MS), ELMOD1 (Proximity Label-MS), DSG4 (Affinity Capture-MS), PBLD (Affinity Capture-MS), ELMOD1 (Affinity Capture-MS), LDHC (Affinity Capture-MS)

ESM2 similar proteins: A1A5Q4, A1L3F5, B0I564, B1AY13, O15327, O75934, Q0IIE6, Q28DG8, Q29RL1, Q2IA00, Q4R4D7, Q4R6T7, Q4R708, Q5NVD7, Q5RA60, Q5RAX7, Q5RBT3, Q5U1Z0, Q5VZE5, Q5ZHV2, Q62717, Q6DDI6, Q6DFL5, Q6DKG0, Q6GLR7, Q6PBE2, Q6PE87, Q6PHQ8, Q7SYB2, Q7T322, Q7ZXA8, Q86UW7, Q86VS3, Q8BMG7, Q8BYR5, Q8C9J3, Q8CDG3, Q8CF97, Q8CJF7, Q8IYR0

Diamond homologs: Q08DZ3, Q09292, Q0IIE6, Q3V1U8, Q54RS7, Q54UP9, Q54VR8, Q54YW1, Q5NVD7, Q5XIQ2, Q8BGF6, Q8IZ81, Q8N336, Q91YP6, Q58DT5

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

56 variants total. Per-class counts are floors (≥ shown; pagination cap):

ClassificationCount (floor)
Pathogenic0
Likely pathogenic0
Uncertain significance40
Likely benign3
Benign1

Top pathogenic / likely-pathogenic (0)

SpliceAI

2656 predictions. Top by Δscore:

VariantEffectΔscore
11:107591437:G:GTdonor_gain1.0000
11:107617914:GC:Gdonor_gain1.0000
11:107618103:A:AGacceptor_gain1.0000
11:107618103:AGTT:Aacceptor_gain1.0000
11:107618104:G:GGacceptor_gain1.0000
11:107618104:GTT:Gacceptor_gain1.0000
11:107618104:GTTG:Gacceptor_gain1.0000
11:107631678:G:GGdonor_gain1.0000
11:107647463:TACA:Tacceptor_loss1.0000
11:107647464:ACAG:Aacceptor_loss1.0000
11:107647465:C:Gacceptor_gain1.0000
11:107647466:A:AGacceptor_gain1.0000
11:107647466:AG:Aacceptor_loss1.0000
11:107647467:G:GAacceptor_gain1.0000
11:107647467:GT:Gacceptor_gain1.0000
11:107647467:GTT:Gacceptor_gain1.0000
11:107647467:GTTA:Gacceptor_gain1.0000
11:107647467:GTTAT:Gacceptor_gain1.0000
11:107647597:TTGCA:Tdonor_gain1.0000
11:107647598:TGCA:Tdonor_gain1.0000
11:107647599:GCA:Gdonor_gain1.0000
11:107647599:GCAG:Gdonor_gain1.0000
11:107647600:CA:Cdonor_gain1.0000
11:107647601:AG:Adonor_loss1.0000
11:107647602:G:GGdonor_gain1.0000
11:107647603:TA:Tdonor_loss1.0000
11:107647604:AAG:Adonor_loss1.0000
11:107647605:AGT:Adonor_loss1.0000
11:107656067:G:GGdonor_gain1.0000
11:107664478:G:GTdonor_gain1.0000

AlphaMissense

2235 scored. Top likely-pathogenic:

VariantProtein changeam_pathogenicity
11:107647522:T:AW159R1.000
11:107647522:T:CW159R1.000
11:107647524:G:CW159C1.000
11:107647524:G:TW159C1.000
11:107647534:G:CG163R1.000
11:107647535:G:AG163D1.000
11:107647535:G:TG163V1.000
11:107647537:T:CF164L1.000
11:107647538:T:CF164S1.000
11:107647539:C:AF164L1.000
11:107647539:C:GF164L1.000
11:107647542:A:CQ165H1.000
11:107647542:A:TQ165H1.000
11:107647552:C:TP169S1.000
11:107647553:C:AP169H1.000
11:107647561:G:CD172H1.000
11:107647562:A:CD172A1.000
11:107647562:A:GD172G1.000
11:107647562:A:TD172V1.000
11:107647563:C:AD172E1.000
11:107647563:C:GD172E1.000
11:107647565:T:CF173S1.000
11:107647576:G:AG177R1.000
11:107647576:G:CG177R1.000
11:107647577:G:AG177E1.000
11:107647577:G:TG177V1.000
11:107655952:G:CG240R1.000
11:107665054:T:AW288R1.000
11:107665054:T:CW288R1.000
11:107665087:T:CF299L1.000

dbSNP variants (sampled 300 via entrez): RS1000002802 (11:107593838 T>C), RS1000108784 (11:107664276 T>C), RS1000151880 (11:107590364 C>G), RS1000156169 (11:107633856 C>G), RS1000209404 (11:107633638 G>A), RS1000211890 (11:107626952 T>G), RS1000217371 (11:107643252 A>C), RS1000259552 (11:107641623 C>T), RS1000263157 (11:107615297 G>A,T), RS1000291101 (11:107664599 T>C), RS1000370518 (11:107640319 A>G), RS1000394911 (11:107610200 C>A,T), RS1000404271 (11:107597996 C>A,T), RS1000445885 (11:107603290 A>G), RS1000482324 (11:107646304 G>A,T)

Disease associations

OMIM: gene MIM:615456 | disease phenotypes:

GenCC curated gene-disease

DiseaseClassificationInheritance
neurodevelopmental disorderLimitedAutosomal recessive

Mondo (1): neurodevelopmental disorder (MONDO:0700092)

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

3 associations (top):

StudyTraitp-value
GCST006168_1Pulse pressure x alcohol consumption interaction (2df test)3.000000e-08
GCST007676_133-month functional outcome in ischaemic stroke (modified Rankin score)4.000000e-06
GCST012485_9Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease7.000000e-06

EFO canonical traits (4, from GWAS)

EFO IDTrait name
EFO:0004329alcohol drinking
EFO:0005763pulse pressure measurement
EFO:0009603stroke outcome severity measurement
EFO:0008343sex interaction measurement

MeSH disease descriptors (1)

DescriptorNameTree numbers
D065886Neurodevelopmental DisordersF03.625

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

43 total (human), top 30 by PubMed support.

ChemicalActions (top 5)PubMed papers
Valproic Acidaffects expression, affects cotreatment, increases expression9
trichostatin Aaffects cotreatment, increases expression3
bisphenol Aincreases methylation, decreases expression2
mercuric bromideincreases expression, affects cotreatment2
entinostatincreases expression, affects cotreatment2
belinostatincreases expression, affects cotreatment2
Panobinostataffects cotreatment, increases expression2
Aflatoxin B1decreases methylation, increases methylation2
sotorasibdecreases expression, affects cotreatment1
propionaldehydeincreases expression1
sodium arsenatedecreases expression, increases abundance1
butyraldehydeincreases expression1
hydroquinoneincreases expression1
S-(1,2-dichlorovinyl)cysteineaffects response to substance, increases expression1
pentanalincreases expression1
CGP 52608increases reaction, affects binding1
deguelindecreases expression1
fenpyroximatedecreases expression1
4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamidedecreases expression1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamideaffects cotreatment, increases expression1
pyrimidifendecreases expression1
clothianidindecreases expression1
ICG 001decreases expression1
thifluzamidedecreases expression1
dorsomorphinaffects cotreatment, increases expression1
trametinibaffects cotreatment, decreases expression1
NVP-BKM120affects cotreatment, decreases expression1
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic aciddecreases expression1
Arsenic Trioxidedecreases expression1
Aldehydesincreases expression1

Clinical trials (associated diseases)

202 trials via MONDO — disease-level, not drug-specific.

TrialPhaseStatusTitle
NCT04586348PHASE4UNKNOWNPrenatal Iodine Supplementation and Early Childhood Neurodevelopment
NCT04873115PHASE4UNKNOWNDouble-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties,
NCT02559102PHASE3COMPLETEDDexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants
NCT02757079PHASE3COMPLETEDStudy of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders
NCT06915480PHASE3RECRUITINGReducing Missed Appointments
NCT07377032PHASE3RECRUITINGTAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders
NCT02909959PHASE2COMPLETEDSulforaphane for the Treatment of Young Men With Autism Spectrum Disorder
NCT06081348PHASE2RECRUITINGSertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
NCT06352372PHASE2COMPLETEDSafety and Efficacy of tPBM for Epileptiform Activity in Autism
NCT00503191PHASE1COMPLETEDNeuroModulation Technique Treatment of Autism
NCT04475848PHASE1COMPLETEDA Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
NCT06300398PHASE1COMPLETEDIAMA-6 Oral Dose Study in Healthy Adults
NCT01783041PHASE2/PHASE3COMPLETEDEffect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
NCT05767385PHASE2/PHASE3RECRUITINGFetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
NCT05675098EARLY_PHASE1NOT_YET_RECRUITINGCentral Nervous System Stimulants and Physical Function in Children With Cerebral Palsy
NCT00783783Not specifiedCOMPLETEDCYP2D6 Pharmacogenetics in Risperidone-Treated Children
NCT01778504Not specifiedRECRUITINGStudying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01850784Not specifiedUNKNOWNHigh Energy Formula Feeding in Infants With Congenital Heart Disease
NCT01922791Not specifiedCOMPLETEDNutrition and Pregnancy Intervention Study
NCT01942525Not specifiedUNKNOWNInfluence of Intrauterine Growth Restriction on Amplitude-integrated EEG in Preterm Infants
NCT02003170Not specifiedCOMPLETEDEtiology and Early Diagnosis of Neurodevelopmental Disorders
NCT02118649Not specifiedACTIVE_NOT_RECRUITINGEnhancing Behavior and Brain Response to Visual Targets Using a Computer Game
NCT02557191Not specifiedTERMINATEDBiomarkers, Neurodevelopment and Preterm Infants
NCT02690675Not specifiedCOMPLETEDIron Supplement Effect on Child Development
NCT02694003Not specifiedCOMPLETEDBetter Nights, Better Days for Children With Neurodevelopment Disorders
NCT02792894Not specifiedCOMPLETEDFamily Networks (FaNs) for Children With Developmental Disorders and Delays
NCT02871674Not specifiedUNKNOWNGood Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial
NCT02887157Not specifiedCOMPLETEDAnalyzing Retinal Microanatomy in ROP
NCT02898298Not specifiedCOMPLETEDPositive Emotion Regulation Training in Children, Adolescents and Young Adults With and Without Developmental Disorder
NCT02912780Not specifiedUNKNOWNIntroduction of Microsystems in a Level 3 Neonatal Intensive Care Unit
NCT03023293Not specifiedCOMPLETEDn-3 PUFAs, Irisin and Maternal Glucose Metabolism From Pregnancy to Postpartum
NCT03023644Not specifiedCOMPLETEDImproving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
NCT03032991Not specifiedUNKNOWNEarly Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
NCT03088189Not specifiedTERMINATEDEffect of Parental Peri-conceptional Vitamin B12 Supplementation on Infant Neurocognitive Development in Offspring
NCT03096028Not specifiedCOMPLETEDDevelopmental Origins of Mental Health Disorders
NCT03148782Not specifiedCOMPLETEDBrain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
NCT03172104Not specifiedCOMPLETEDNeurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age
NCT03222375Not specifiedRECRUITINGSQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism
NCT03229928Not specifiedCOMPLETEDClinical Testing of a Real-Time Behavior Measurement Tool: Measuring Outcomes for CHAnge
NCT03232489Not specifiedUNKNOWNStudy for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice